Protein Alignment H15 and tbx21

DIOPT Version :10

• Sequence 1: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_002940203.2
• Gene: tbx21 / 100496799
• XenbaseID: XB-GENE-479103
• Length: 561
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 177/612 - (28%)
• Similarity: 240/612 - (39%)
• Gaps: 126/612 - (20%)

  Fly    90 GGNAPSSREPSERSLSPASVERYSGQDADDDVDVDVVDCSDSEMPSATAAAAAAATTAAAAAAAL 154
            |...|.:..|.:.:....|..|..|.......|:..:....|:|...:...|.:||....|
 Frog    19 GMQGPPTVPPMKSAGELQSTVRLPGTARLQKTDMQSIIKLQSKMTMQSIKDAQSATELHGA---- 79

  Fly   155 QAQQQARQALRVAQQQQQQQQ------QQRQQTHHHATTGKQQRQHHNHHSSNTNNSSNSGNSNT 213
             .:.|.|..|.....:....:      |.|::.|..|.......:.|.:      ..||||..|.
 Frog    80 -TETQNRTDLHRTMSKHNTVEMPNGAMQSREELHSGADVQSLPTEQHKY------CQSNSGEDNL 137

  Fly   214 N-SKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIV----------G 267
            | :.|...|.|...:...:.|       ...|||..|.::..|..|:.|.|..:          |
 Frog   138 NPTFSFPSRIRLLPSSSCSYT-------QEYSPEGAEAVNYSERDAELPYPLSLQHALPHTNPSG 195

  Fly   268 SCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLD 332
            :..|.....||..|....||||||:..|||||||.||||||.:....:|    :.|..:|.:.:|
 Frog   196 TPECQRSGKVQITLTNYSLWDKFHKHQTEMIITKQGRRMFPFLSFRVAG----LDPVAQYNLHVD 256

  Fly   333 VVPLDSRRYRYAYHRSSWLVAGKAD-PPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNE--- 393
            ||..|...:|  |....|...|||: ..|.:|.|.|||.|.:.....:|.|.|.|:|||||:
 Frog   257 VVLADQNHWR--YQGGKWTQCGKAEGNMPGNRTYQHPDSPNTGAHWMRQEVIFSKLKLTNNKGAS 319

  Fly   394 MDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITK 458
            .:.|..|||.|:|:||||.|:.|:..    ||.|   :...| :|:||||.|.|||||||..||:
 Frog   320 NNVSQMVVLQSLHKYQPRFHVTRVED----PGGP---ESQSH-SFIFPETQFIAVTAYQNADITQ 376

  Fly   459 LKIDSNPFAKGFRD----------SSRLSDFDRDPMDAFFFDQHMRTAPLR---FFPDPLMSQLT 510
            ||||.|||||||||          ..|:|.                :.|:|   :..:|:.|
 Frog   377 LKIDHNPFAKGFRDHCDLMCLTPNGERVSP----------------SPPVRYTNYLQEPVPS--- 422

  Fly   511 PQEADAASMALLEKARQHLQMFGRSPYTEMLLPHLYQRSAAPPPPPPAPHLSAFQLGMWQQQWPQ 575
               |...|:...|....:|.....:|..|.            ||..||..::|:.:..:.|..|
 Frog   423 ---ARLFSVEQKEPPSWYLSSQNIAPQLEY------------PPYDPAGKMAAYAMKCYPQPSP- 471

  Fly   576 LTAGFLASANQQAALALAAAG-ANRTPPPSMAVAPPAP---ATPTSSCGSASPDLRARPQLNHYP 636
                  .|...:..|..|..| |...|.||     |||   ..|.........|..|......|.
 Frog   472 ------LSYYPEHTLTSAWGGPAQYHPKPS-----PAPLGWLRPLLEVQKKEEDSCAWGDTTTYA 525

  Fly   637 -------QRFSPYQVPQHQASPPASNR 656
                   :|.|||   ....||..:.|
 Frog   526 GYEDSKRRRLSPY---SSDGSPQMTER 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
H15	NP_608926.2	T-box_TBX20-like	277..473	CDD:410319	95/209 (45%)
tbx21	XP_002940203.2	T-box	204..390	CDD:469628	93/199 (47%)