DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nompC and ANK1

DIOPT Version :9

Sequence 1:	NP_523483.2	Gene:	nompC / 33768	FlyBaseID:	FBgn0016920	Length:	1761	Species:	Drosophila melanogaster
Sequence 2:	NP_001331981.1	Gene:	ANK1 / 831855	AraportID:	AT5G02620	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	627	Identity:	138/627 - (22%)
Similarity:	244/627 - (38%)	Gaps:	155/627 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   807 EVAKLFLQQHPSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGV----ISARNKLTDATPL 867
            |:.|...:|      .|::..:|..|.|..:|...::.|::. :..||    :.|....:..|.|
plant     3 EIKKTMTKQ------MTARRDDTPLHTAVREGKTDLLLEMIG-EHDGVELKELLAEQNQSGETAL 60

  Fly   868 QLAAEGGHADVVKALVRAGASCTEENKA--GFTAVHLAAQNGHGQVLDVLKSTN---SLRINSKK 927
            .:|||.|:.|:||.|::...|.....||  ||.|.|:||:||:.||||||...|   |...:|.|
plant    61 YVAAEYGYTDMVKILMKHSDSVLAGTKAKNGFDAFHIAAKNGNLQVLDVLIEANPELSFTFDSSK 125

  Fly   928 LGLTPLHVAAYYGQADTVRELLTSVPATVKSETPTGQSLFGDLGTESGMTPLHLAAFSGNENVVR 992
                                                            .|.||.||..|:..:|.
plant   126 ------------------------------------------------TTALHTAASQGHGEIVC 142

  Fly   993 LLLNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSRSAELLQSQDRNGRTGLHIAAMHGHI 1057
            .||:. ||.:.|....||...||.|...||..:|..|:.:.|.::...|:.|:|.||:|....:.
plant   143 FLLDK-GVDLAAIARSNGKTALHSAARNGHTVIVKKLIEKKAGMVTRVDKKGQTALHMAVKGQNT 206

  Fly  1058 QMVEILL-GQGAEINATDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEG 1121
            ::|::|: ..|:.||:.|..|.||||.|.:....||:
plant   207 EIVDVLMEADGSLINSADNKGNTPLHIAVRKNRAEVI---------------------------- 243

  Fly  1122 HNEVLRYLMNKEHDTYGLMEDKRFVYNLMVVSKNHNNKPIQEFVLVSPAPVDTAAKLSNIYIVLS 1186
                    :::....:.|.:.:.|:|:|.:|      :.:.::..||...|:.:.:.:     |.
plant   244 --------VDQSFKLFLLQKLESFLYSLQIV------QTVLKYCEVSRVAVNKSGETA-----LD 289

  Fly  1187 TKEKERAKDLV----AAGKQCEAMATELLALAAGSDSAGKILQATDKRNVEFLDVLIENEQ---- 1243
            ..||....::|    ..|.| .|.:.:.......|.|:.|:.:...:...|   |..:.||
plant   290 IAEKTGLHEIVPLLQKIGMQ-NARSIKPAEKVEPSGSSRKLKETVSEIGHE---VHTQLEQTGRT 350

  Fly  1244 -KEV--IAHTVVQRYLQELWHGSLTWASWKILLLLVAFIVCPPVWIGFT-----FPMGHKFNK-- 1298
             :|:  ||..|.:.:.:.|.:...:.....||:..|||.....|...:|     .|.|:...:
plant   351 RREIQGIAKRVNKMHTEGLNNAINSTTLVAILIATVAFAAIFNVPGQYTDDPKDVPPGYSLGEAR 415

  Fly  1299 -VPIIKFMSYLTSHIY-LMIHLSIVGI-TPIYPVLRLSLVPYWYEVGLLIWLSGLLL-------- 1352
             .|..:|:.::....: |.|.|::|.: |.:..:.|.:.......:..|:|::.:::
plant   416 AAPRPEFLIFVVFDSFALFISLAVVVVQTSVVVIERRAKKQMMAIINKLMWMACIMISVAFVSLS 480

  Fly  1353 FELTNPSDKSGLGSIKVLVLLLGMAGVGVHVSAFLFVSKEYW 1394
            |.:....:|.         |.:|:..:|..:......:..||
plant   481 FVVVGEKEKP---------LAVGVTAIGALIMVSTLGTMCYW 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nompC	NP_523483.2	ANK repeat	129..157	CDD:293786
		Ank_2	131..228	CDD:289560
		ANK	155..319	CDD:238125
		ANK repeat	159..186	CDD:293786
		ANK repeat	232..265	CDD:293786
		Ank_2	237..331	CDD:289560
		ANK	263..387	CDD:238125
		ANK repeat	267..298	CDD:293786
		ANK repeat	300..331	CDD:293786
		Ank_2	305..398	CDD:289560
		ANK	329..454	CDD:238125
		ANK repeat	367..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		Ank_2	405..498	CDD:289560
		ANK	428..555	CDD:238125
		ANK repeat	433..463	CDD:293786
		ANK repeat	469..499	CDD:293786
		ANK	496..641	CDD:238125
		ANK repeat	501..532	CDD:293786
		Ank_2	507..616	CDD:289560
		ANK repeat	534..575	CDD:293786
		ANK repeat	577..616	CDD:293786
		Ank_2	625..722	CDD:289560
		ANK	654..780	CDD:238125
		ANK repeat	660..690	CDD:293786
		ANK repeat	692..723	CDD:293786
		Ank_2	697..790	CDD:289560
		ANK	720..847	CDD:238125	9/39 (23%)
		ANK repeat	725..757	CDD:293786
		ANK repeat	759..790	CDD:293786
		Ank_5	779..834	CDD:290568	6/26 (23%)
		ANK	787..915	CDD:238125	37/113 (33%)
		ANK repeat	792..824	CDD:293786	3/16 (19%)
		ANK repeat	861..893	CDD:293786	11/31 (35%)
		Ank_4	865..915	CDD:290365	25/51 (49%)
		Ank_4	929..995	CDD:290365	7/65 (11%)
		ANK repeat	932..972	CDD:293786	0/39 (0%)
		ANK	969..1096	CDD:238125	42/127 (33%)
		ANK repeat	974..1007	CDD:293786	12/32 (38%)
		Ank_2	979..1074	CDD:289560	32/95 (34%)
		ANK repeat	1009..1041	CDD:293786	10/31 (32%)
		ANK	1039..1159	CDD:238125	25/120 (21%)
		ANK repeat	1043..1074	CDD:293786	10/31 (32%)
		Ank_2	1048..1135	CDD:289560	17/87 (20%)
		ANK repeat	1076..1101	CDD:293786	8/24 (33%)
		ANK repeat	1109..1134	CDD:293786	0/24 (0%)
		Ion_trans	<1393..1598	CDD:278921	2/2 (100%)
ANK1	NP_001331981.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8400
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910