DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment nompC and KEG

DIOPT Version :9

Sequence 1:NP_523483.2 Gene:nompC / 33768 FlyBaseID:FBgn0016920 Length:1761 Species:Drosophila melanogaster
Sequence 2:NP_196857.2 Gene:KEG / 831197 AraportID:AT5G13530 Length:1625 Species:Arabidopsis thaliana


Alignment Length:925 Identity:201/925 - (21%)
Similarity:302/925 - (32%) Gaps:360/925 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 DSSSNGDKKDMDLFPAPKPPSAGASIRDTANKVLGL-----AMKSEWTPIEA--ELKKLEKYVAN 108
            |:|.|....|..|.|..|.|:...:..:..:..:.|     .:...:|..||  .:|||      
plant   278 DASGNAVVSDYGLAPILKKPTCQKTRPEFDSSKVTLYTDCVTLSPHYTAPEAWGPVKKL------ 336

  Fly   109 VGEDGNHIPLAGVH-------------DMNTGMTPLMYATKDNKTAIMDRMIELGADVGARNNDN 160
            ..||.     :||.             :|.||.||            .|.:              
plant   337 FWEDA-----SGVSPESDAWSFGCTLVEMCTGSTP------------WDGL-------------- 370

  Fly   161 YNVLHIAAMYSREDVVKLLLTKRGVDPFSTGGSRSQTAVHLVSSRQTGTATNILRALLAAAGKDI 225
                      |||::.:.::..|.|.|                ..:......|.|.|....|:.:
plant   371 ----------SREEIFQAVVKARKVPP----------------QYERIVGVGIPRELWKMIGECL 409

  Fly   226 RLKADGRGKIPLLLAVESGNQSMCRELLAAQTAEQLKATTANGDTALHLAARRRDVDMVRILVDY 290
            :.|...|.....:||      :..|.|     .|..::.:|:.|..:   |:..:|::|:  ...
plant   410 QFKPSKRPTFNAMLA------TFLRHL-----QEIPRSPSASPDNGI---AKICEVNIVQ--APR 458

  Fly   291 GTNV----DTQNGEGQTPLHIAAAEGDEALLKYFYGVRASASIADNQDRTPMHLAAENGHAHVIE 351
            .||:    |..|.     ||....|||      |.|||...:.|          ||..|      
plant   459 ATNIGVFQDNPNN-----LHRVVLEGD------FEGVRNILAKA----------AAGGG------ 496

  Fly   352 ILADKFKASIFERTKDGSTLMHIASLNGHAECATMLFKKGVYLHMPNKDGARSIHTAAAYGHTGI 416
                            ||::..:                   |...|.||..::|.|...|...:
plant   497 ----------------GSSVRSL-------------------LEAQNADGQSALHLACRRGSAEL 526

  Fly   417 INTLLQKGE-KVDVTTNDNYTALHIAVESAKPAVVETLLGFGADVHVRGGKLRETPLHIAARVKD 480
            :..:|:.|| .||:...|....|..|:.:..|..|..|:..||:|..|                 
plant   527 VEAILEYGEANVDIVDKDGDPPLVFALAAGSPQCVHVLIKKGANVRSR----------------- 574

  Fly   481 GDRCALMLLKSGASPNLTTDDCLTPVHVAARHGNLATLMQLLEDEGDPLYKSNTGETPLHMACRA 545
                    |:.|:.|::        .||.:.||                                
plant   575 --------LREGSGPSV--------AHVCSYHG-------------------------------- 591

  Fly   546 CHPDIVRHLIETVKEKHGPDKATTYINSVNEDGATALH------YT-CQITKEEVKIPESDKQIV 603
             .||.:|.|:..     |.|.     |:|:::|.|.||      || |.|               
plant   592 -QPDCMRELLVA-----GADP-----NAVDDEGETVLHRAVAKKYTDCAI--------------- 630

  Fly   604 RMLLENGADVTLQTKTA-LETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIA 667
             ::||||...::....| ..|..|.|....|..|:...:...:|.:|.:|:|..|.|| |.|.:|
plant   631 -VILENGGSRSMTVSNAKCLTPLHMCVATWNVAVIKRWVEVSSPEEISQAINIPSPVG-TALCMA 693

  Fly   668 C--HRGH----MELVNNLLANHARVDVFDTEGRSALHLAAERGYLHVCDALLTNKAFINSKSRVG 726
            .  .:.|    .|||..|||..|     |...:.|.|                           |
plant   694 ASIRKDHEKEGRELVQILLAAGA-----DPTAQDAQH---------------------------G 726

  Fly   727 RTALHLAAMNGFTHLVKFLIKDHNAVIDILTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDD 791
            |||||.|||.....||: :|.|.....:|..:....|||:|.|.|......||||.|::.:..||
plant   727 RTALHTAAMANNVELVR-VILDAGVNANIRNVHNTIPLHMALARGANSCVSLLLESGSDCNIQDD 790

  Fly   792 LGQKPIHVAAQNNYSEVAKLFLQQHPSL-VNATSKDGNTCAHIAAMQGSVKVIEELMKFDRSGVI 855
            .|....|:||     :.||:..:....| |...|.|    |.:.....|.|.:.:.:        
plant   791 EGDNAFHIAA-----DAAKMIRENLDWLIVMLRSPD----AAVDVRNHSGKTVRDFL-------- 838

  Fly   856 SARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNS 920
                   :|.|.:..:|    |:::||::.|             |||:..  ..:|.|.:|.   
plant   839 -------EALPREWISE----DLMEALLKRG-------------VHLSPT--IYEVGDWVKF--- 874

  Fly   921 LRINSKKLGL-TPLH 934
                  |.|: ||||
plant   875 ------KRGITTPLH 883

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nompCNP_523483.2 ANK repeat 129..157 CDD:293786 3/27 (11%)
Ank_2 131..228 CDD:289560 11/96 (11%)
ANK 155..319 CDD:238125 31/167 (19%)
ANK repeat 159..186 CDD:293786 4/26 (15%)
ANK repeat 232..265 CDD:293786 6/32 (19%)
Ank_2 237..331 CDD:289560 23/97 (24%)
ANK 263..387 CDD:238125 24/127 (19%)
ANK repeat 267..298 CDD:293786 7/34 (21%)
ANK repeat 300..331 CDD:293786 9/30 (30%)
Ank_2 305..398 CDD:289560 16/92 (17%)
ANK 329..454 CDD:238125 23/125 (18%)
ANK repeat 367..398 CDD:293786 3/30 (10%)
ANK repeat 400..431 CDD:293786 10/31 (32%)
Ank_2 405..498 CDD:289560 21/93 (23%)
ANK 428..555 CDD:238125 21/126 (17%)
ANK repeat 433..463 CDD:293786 9/29 (31%)
ANK repeat 469..499 CDD:293786 3/29 (10%)
ANK 496..641 CDD:238125 30/152 (20%)
ANK repeat 501..532 CDD:293786 4/30 (13%)
Ank_2 507..616 CDD:289560 24/115 (21%)
ANK repeat 534..575 CDD:293786 7/40 (18%)
ANK repeat 577..616 CDD:293786 12/45 (27%)
Ank_2 625..722 CDD:289560 25/102 (25%)
ANK 654..780 CDD:238125 39/131 (30%)
ANK repeat 660..690 CDD:293786 12/35 (34%)
ANK repeat 692..723 CDD:293786 2/30 (7%)
Ank_2 697..790 CDD:289560 26/92 (28%)
ANK 720..847 CDD:238125 40/127 (31%)
ANK repeat 725..757 CDD:293786 14/31 (45%)
ANK repeat 759..790 CDD:293786 11/30 (37%)
Ank_5 779..834 CDD:290568 17/55 (31%)
ANK 787..915 CDD:238125 27/128 (21%)
ANK repeat 792..824 CDD:293786 8/32 (25%)
ANK repeat 861..893 CDD:293786 7/31 (23%)
Ank_4 865..915 CDD:290365 11/49 (22%)
Ank_4 929..995 CDD:290365 5/7 (71%)
ANK repeat 932..972 CDD:293786 3/3 (100%)
ANK 969..1096 CDD:238125
ANK repeat 974..1007 CDD:293786
Ank_2 979..1074 CDD:289560
ANK repeat 1009..1041 CDD:293786
ANK 1039..1159 CDD:238125
ANK repeat 1043..1074 CDD:293786
Ank_2 1048..1135 CDD:289560
ANK repeat 1076..1101 CDD:293786
ANK repeat 1109..1134 CDD:293786
Ion_trans <1393..1598 CDD:278921
KEGNP_196857.2 RING-HC_ScPSH1_like 9..56 CDD:319482
RING-HC finger (C3HC4-type) 10..55 CDD:319482
S_TKc 138..424 CDD:214567 37/208 (18%)
ANKYR <427..571 CDD:223738 47/215 (22%)
ANK repeat 472..508 CDD:293786 16/92 (17%)
ANK repeat 510..542 CDD:293786 10/31 (32%)
PHA03095 517..>857 CDD:222980 117/493 (24%)
ANK repeat 544..575 CDD:293786 10/55 (18%)
ANK repeat 577..610 CDD:293786 13/83 (16%)
ANK repeat 688..722 CDD:293786 12/38 (32%)
ANK repeat 725..756 CDD:293786 15/58 (26%)
ANK repeat 758..789 CDD:293786 11/30 (37%)
ANK repeat 791..828 CDD:293786 11/45 (24%)
SH3_15 909..984 CDD:375773
SH3_15 1053..1110 CDD:375773
SH3_15 1116..1166 CDD:375773
SH3_15 1242..1363 CDD:375773
SH3_15 1426..1488 CDD:375773
SH3_15 1560..1617 CDD:375773
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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