DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment nompC and AT2G01680

DIOPT Version :9

Sequence 1:	NP_523483.2	Gene:	nompC / 33768	FlyBaseID:	FBgn0016920	Length:	1761	Species:	Drosophila melanogaster
Sequence 2:	NP_565274.1	Gene:	AT2G01680 / 814697	AraportID:	AT2G01680	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	615	Identity:	135/615 - (21%)
Similarity:	218/615 - (35%)	Gaps:	189/615 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   713 LTNKAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDILTLRKQTPLHLAAASGQMEVCQ 777
            ||::||.:|        :....::....||..|..|.  :||     :.:|            |.
plant     9 LTHQAFFSS--------VRSGDLSQLQQLVDNLTGDE--LID-----ESSP------------CS 46

  Fly   778 LLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLFLQQHPSL--VNATSKDGNTCAHIAAMQGSV 840
            .:.||   :...:|.|:..::::|..|..::.: :|.:..||  |...||......|:||.:|.:
plant    47 AVAEL---MSVQNDAGETAVYISAAENLEDIFR-YLIRFSSLETVKIRSKSDMNAFHVAAKRGHL 107

  Fly   841 KVIEELMKF--DRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLA 903
            .:::||::.  :...:..|.|    .:||..||...|.::|.|::....||.
plant   108 GIVKELLRLWPELCRICDASN----TSPLYAAAVQDHLEIVNAMLDVDPSCA------------- 155

  Fly   904 AQNGHGQVLDVLKSTNSLRINSKKLGLTPLHVAAYYGQADTVRELLTSVPATVKSETPTGQSLFG 968
                               :..:|.|.|.||.|..||       ||..|.|.::.:
plant   156 -------------------MIVRKNGKTSLHTAGRYG-------LLRIVKALIEKD--------- 185

  Fly   969 DLGTESGMTPLHLAAFSGNENVVRLLLNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSRS 1033
                         ||..|.::                  :.|...||:|..|..:.||..:|...
plant   186 -------------AAIVGVKD------------------KKGQTALHMAVKGRSLEVVEEILQAD 219

  Fly  1034 AELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQGA-EINATDRNGWTPLHCAAKAGH----LEVV 1093
            ..:|..:||.|.|.||||......|:..:||...| |:||.:....|.:..|.|..:    ||:.
plant   220 YTILNERDRKGNTALHIATRKARPQITSLLLTFTAIEVNAINNQKETAMDLADKLQYSESALEIN 284

  Fly  1094 KLLCEAGASPKSETNYG--------CAAIWFAASEGHNEVLRYLMNKE---HDTYGLMEDKRFVY 1147
            :.|.||||      .:|        ..|:..|.|:..:||...|:..|   ....|:.::.|.::
plant   285 EALVEAGA------KHGRFIGREDEARALKRAVSDIKHEVQSQLLQNEKTNRRVSGIAKELRKLH 343

  Fly  1148 NLMVVSKNHNNKPIQEFVLVSPAPVDTAAKLSNIYIVLSTKEKERAKDLVAAGKQ-----CEAMA 1207
            ...|  :|..|......||.:.........|...|..    |.........||:.     |...|
plant   344 REAV--QNTTNSITVVAVLFASIAFLAIFNLPGQYFT----EGSHVGQANIAGRTGFRVFCLLNA 402

  Fly  1208 TEL-LALAAGSDSAGKILQAT----DKRNVEFLDVLIENEQKEVIAHTVVQRYLQELWHGSLTWA 1267
            |.| ::||.      .::|.|    |.|           .||:|:  :||.:         |.||
plant   403 TSLFISLAV------VVVQITLVAWDTR-----------AQKKVV--SVVNK---------LMWA 439

  Fly  1268 SWKI---LLLLVAFIVCPP--VWIGFTFPM 1292
            :...   ..|.:||.|...  .|:..|..:
plant   440 ACACTFGAFLAIAFAVVGKGNSWMAITITL 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nompC	NP_523483.2	ANK repeat	129..157	CDD:293786
		Ank_2	131..228	CDD:289560
		ANK	155..319	CDD:238125
		ANK repeat	159..186	CDD:293786
		ANK repeat	232..265	CDD:293786
		Ank_2	237..331	CDD:289560
		ANK	263..387	CDD:238125
		ANK repeat	267..298	CDD:293786
		ANK repeat	300..331	CDD:293786
		Ank_2	305..398	CDD:289560
		ANK	329..454	CDD:238125
		ANK repeat	367..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		Ank_2	405..498	CDD:289560
		ANK	428..555	CDD:238125
		ANK repeat	433..463	CDD:293786
		ANK repeat	469..499	CDD:293786
		ANK	496..641	CDD:238125
		ANK repeat	501..532	CDD:293786
		Ank_2	507..616	CDD:289560
		ANK repeat	534..575	CDD:293786
		ANK repeat	577..616	CDD:293786
		Ank_2	625..722	CDD:289560	4/8 (50%)
		ANK	654..780	CDD:238125	13/66 (20%)
		ANK repeat	660..690	CDD:293786
		ANK repeat	692..723	CDD:293786	5/9 (56%)
		Ank_2	697..790	CDD:289560	15/76 (20%)
		ANK	720..847	CDD:238125	26/128 (20%)
		ANK repeat	725..757	CDD:293786	6/31 (19%)
		ANK repeat	759..790	CDD:293786	4/30 (13%)
		Ank_5	779..834	CDD:290568	13/56 (23%)
		ANK	787..915	CDD:238125	27/131 (21%)
		ANK repeat	792..824	CDD:293786	7/33 (21%)
		ANK repeat	861..893	CDD:293786	9/31 (29%)
		Ank_4	865..915	CDD:290365	9/49 (18%)
		Ank_4	929..995	CDD:290365	14/65 (22%)
		ANK repeat	932..972	CDD:293786	9/39 (23%)
		ANK	969..1096	CDD:238125	32/131 (24%)
		ANK repeat	974..1007	CDD:293786	3/32 (9%)
		Ank_2	979..1074	CDD:289560	27/95 (28%)
		ANK repeat	1009..1041	CDD:293786	9/31 (29%)
		ANK	1039..1159	CDD:238125	37/135 (27%)
		ANK repeat	1043..1074	CDD:293786	13/31 (42%)
		Ank_2	1048..1135	CDD:289560	29/102 (28%)
		ANK repeat	1076..1101	CDD:293786	8/28 (29%)
		ANK repeat	1109..1134	CDD:293786	8/35 (23%)
		Ion_trans	<1393..1598	CDD:278921
AT2G01680	NP_565274.1	Ank_2	<52..114	CDD:403870	15/62 (24%)
		ANK repeat	59..91	CDD:293786	7/32 (22%)
		ANK repeat	97..125	CDD:293786	6/27 (22%)
		Ank_2	98..186	CDD:403870	29/152 (19%)
		ANK repeat	127..156	CDD:293786	10/64 (16%)
		ANK repeat	161..193	CDD:293786	14/60 (23%)
		Ank_2	166..250	CDD:403870	30/130 (23%)
		ANK repeat	195..227	CDD:293786	9/31 (29%)
		ANK repeat	229..261	CDD:293786	13/31 (42%)
		PGG	345..455	CDD:404788	31/143 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910