DRSC/TRiP Functional Genomics Resources

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Protein Alignment nompC and Ankrd53

DIOPT Version :9

Sequence 1:NP_523483.2 Gene:nompC / 33768 FlyBaseID:FBgn0016920 Length:1761 Species:Drosophila melanogaster
Sequence 2:NP_083521.2 Gene:Ankrd53 / 75305 MGIID:1922555 Length:497 Species:Mus musculus


Alignment Length:379 Identity:79/379 - (20%)
Similarity:133/379 - (35%) Gaps:109/379 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   238 LLAVESGNQSMCRELLAAQTAEQLKATTANGDTALHLAARRRDVDMVRILV-DYGTNVDTQNGEG 301
            |.|...||....|..:..:..|.:  ....|.||:|.||::..:..:::|: :|...||....:|
Mouse    83 LFAASVGNVDWLRFCVNPERKEII--VDDKGFTAIHFAAQKCQLSCLKVLIEEYKYPVDLPTNKG 145

  Fly   302 QTPLHIAAAEGDEALLKYFYGVRASASIADNQDRTPMHLAAENGHAHVIEILADKFKASIFERTK 366
            |||||:...:.:::                  |..|           .|:.|..| .|:|..:|.
Mouse   146 QTPLHLVIHKNNKS------------------DILP-----------CIDYLLKK-GAAINSQTY 180

  Fly   367 DGSTLMHIASLNGHAECATMLFKKGVYLHMPNKDGARSIHTAAAYGHTGII------------NT 419
            :|||.:|:||.||...|..:|.:.|..:|..:..|.:.|.....:.|....            ..
Mouse   181 NGSTPLHLASCNGLLGCIKLLVQSGANVHARDATGFKPIDYCRLWNHRTCARFLKDVMWKHDKKV 245

  Fly   420 LLQKGEKVDVTTNDNYTAL--HIAVESAKPAVVETLLGFGADVHVRGGKLRETPLH-------IA 475
            |.|:.||:. |..:..|.|  |..||..|...:                |||....       :|
Mouse   246 LAQEMEKLR-TLKEKLTILEYHYLVEYQKEHQI----------------LREAHFRKWLQNKVLA 293

  Fly   476 ARVKDGDRCALMLLKSGASP-NLTTDDCLTPVHVAARHGNLATLMQLLED---EGDPLYK----- 531
            ..:...|    ...|:|..| :|.::....|:..:..:.::...::.|..   ...|:||     
Mouse   294 QTLGSAD----SKQKAGVQPWSLASNTLRCPITESLHYPSVEAQLKNLPSPVVPPKPIYKQTTIS 354

  Fly   532 --------SNTGETPLHMACRACHPDIV--------------RHLIETVKEKHG 563
                    :|...:|:   ....||..:              |..:|..:.|||
Mouse   355 RPKLWNYSANPARSPI---TNIGHPQNIRLGVHPEPYKEHDFRRFLEVTRNKHG 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nompCNP_523483.2 ANK repeat 129..157 CDD:293786
Ank_2 131..228 CDD:289560
ANK 155..319 CDD:238125 22/81 (27%)
ANK repeat 159..186 CDD:293786
ANK repeat 232..265 CDD:293786 6/26 (23%)
Ank_2 237..331 CDD:289560 22/93 (24%)
ANK 263..387 CDD:238125 33/124 (27%)
ANK repeat 267..298 CDD:293786 10/31 (32%)
ANK repeat 300..331 CDD:293786 6/30 (20%)
Ank_2 305..398 CDD:289560 22/92 (24%)
ANK 329..454 CDD:238125 34/138 (25%)
ANK repeat 367..398 CDD:293786 12/30 (40%)
ANK repeat 400..431 CDD:293786 7/42 (17%)
Ank_2 405..498 CDD:289560 21/114 (18%)
ANK 428..555 CDD:238125 26/166 (16%)
ANK repeat 433..463 CDD:293786 6/31 (19%)
ANK repeat 469..499 CDD:293786 7/37 (19%)
ANK 496..641 CDD:238125 15/98 (15%)
ANK repeat 501..532 CDD:293786 5/46 (11%)
Ank_2 507..616 CDD:289560 13/87 (15%)
ANK repeat 534..575 CDD:293786 8/44 (18%)
ANK repeat 577..616 CDD:293786
Ank_2 625..722 CDD:289560
ANK 654..780 CDD:238125
ANK repeat 660..690 CDD:293786
ANK repeat 692..723 CDD:293786
Ank_2 697..790 CDD:289560
ANK 720..847 CDD:238125
ANK repeat 725..757 CDD:293786
ANK repeat 759..790 CDD:293786
Ank_5 779..834 CDD:290568
ANK 787..915 CDD:238125
ANK repeat 792..824 CDD:293786
ANK repeat 861..893 CDD:293786
Ank_4 865..915 CDD:290365
Ank_4 929..995 CDD:290365
ANK repeat 932..972 CDD:293786
ANK 969..1096 CDD:238125
ANK repeat 974..1007 CDD:293786
Ank_2 979..1074 CDD:289560
ANK repeat 1009..1041 CDD:293786
ANK 1039..1159 CDD:238125
ANK repeat 1043..1074 CDD:293786
Ank_2 1048..1135 CDD:289560
ANK repeat 1076..1101 CDD:293786
ANK repeat 1109..1134 CDD:293786
Ion_trans <1393..1598 CDD:278921
Ankrd53NP_083521.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..65
ANK 106..234 CDD:238125 39/159 (25%)
ANK 1 110..140 9/29 (31%)
ANK repeat 111..142 CDD:293786 10/30 (33%)
Ank_2 115..212 CDD:289560 33/126 (26%)
ANK repeat 144..179 CDD:293786 13/64 (20%)
ANK 2 144..177 13/62 (21%)
ANK repeat 181..212 CDD:293786 12/30 (40%)
ANK 3 181..210 11/28 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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