DRSC/TRiP Functional Genomics Resources

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Protein Alignment nompC and ripk4

DIOPT Version :10

Sequence 1:NP_523483.2 Gene:nompC / 33768 FlyBaseID:FBgn0016920 Length:1761 Species:Drosophila melanogaster
Sequence 2:XP_002941332.1 Gene:ripk4 / 733737 XenbaseID:XB-GENE-494474 Length:717 Species:Xenopus tropicalis


Alignment Length:791 Identity:178/791 - (22%)
Similarity:281/791 - (35%) Gaps:255/791 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   334 DRTPMHLAAENGHAHVIEILADKFKASIFERTK-DGSTLMHIASLNGHAECATMLFKKGVYLHMP 397
            |..|.::..: ||.||        |.|.|...| :|.:..|..||:|  .|.|:.:       :|
 Frog   143 DLKPANILLD-GHYHV--------KISDFGLAKWNGLSNSHELSLDG--ICGTIAY-------LP 189

  Fly   398 NKDGARSIHTAAAYGHTGIINTLLQKGEKVDVTTNDNYT-ALHI--AVESAKPAVVETLLGFGAD 459
            .:                   ...:|....| |.:|.|: |:.|  .:...||        |..:
 Frog   190 PE-------------------RFKEKNRSFD-TKHDVYSFAIVIWGILAQRKP--------FAEE 226

  Fly   460 VHVRGGKLRETPLHIAARVKDGDRCALMLLKSGASPNLTTDDCLTPVHVAARHGNLATLMQLLED 524
            .::         |||..:|..|.|..|..:     |.:....|         .|.:..:.:...|
 Frog   227 KNI---------LHIMVKVGGGLRPDLSQI-----PRVRPQQC---------QGMIQLMKECWHD 268

  Fly   525 EGD--PLYKSNTGETPLHMACRACHPDIVRHLIET----VKEKHGPDKATTYINSVNEDGATALH 583
            :.|  |.::..|.||. |:..:  |.|      ||    .:|.||  |.|....:.|. |:.|  
 Frog   269 KPDKRPTFQEITSETE-HLCTK--HED------ETSCVQAQELHG--KGTLDAEAENV-GSQA-- 319

  Fly   584 YTCQITKEEVKIPESDKQIVRML--LENGADVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNP 646
               :..:......:.|..:..:|  |::|...|::                ....|...:|....
 Frog   320 ---ECKRSPTPAFDKDYSLSELLSQLDSGISQTME----------------GPGCLSHSVSEPQL 365

  Fly   647 TDIQKAMNRQSSVGWTPLLIACHRGHMELVNNLLANHARVDVFDTEGRSALHLAAERGYLHVCDA 711
            ....|.::..|||.                          ..|.:.|  :|.|:.|:.    |..
 Frog   366 ASSDKRLSGVSSVD--------------------------SAFSSRG--SLSLSFEKD----CSV 398

  Fly   712 LLTNKAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDILTLRKQTPLHLAAASGQMEVC 776
            |..:...|..|..:.      |...|.|..:..:::..:  :|::...:.:.||||..:||.|..
 Frog   399 LDISANDIQKKKLID------AIAGGDTAKLMKILQPQD--VDLVLEGRSSLLHLAVENGQEECA 455

  Fly   777 QLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLFLQQHPSLVNATSKDGNTCAHIAAMQGSVK 841
            :|||...|:.:.|:..|..|:|:||......:.:|.|.:.   :|..:||               
 Frog   456 KLLLLYNASPNMTNLKGSTPLHIAADKKLKNIVELLLGKK---INVNAKD--------------- 502

  Fly   842 VIEELMKFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQN 906
                                                             |::   |||:|.:|||
 Frog   503 -------------------------------------------------EDH---FTALHFSAQN 515

  Fly   907 GHGQVLDVL--KSTNSLRINSKKLGLTPLHVAAYYGQADTVRELL-TSVPATVKSETPTGQSLFG 968
            |...:..:|  ||.:...::.|  |.||||||..:||.:.||..| .....|.|.          
 Frog   516 GDECITRMLLEKSASLNEVDIK--GRTPLHVACQHGQENIVRVFLRREADLTFKG---------- 568

  Fly   969 DLGTESGMTPLHLAAFSGNENVVRLLLNSAGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSRS 1033
                :.....||.||:.|:.|:||||....|..::|.| .:|..|||||...||..|..:|:...
 Frog   569 ----QDNWLALHYAAWQGHLNIVRLLAKQPGANINAQT-SDGRTPLHLAAQRGHYRVARILVDLR 628

  Fly  1034 AE-----LLQSQDRNGRTGLHIAAMHGHIQMVEILLGQGAEINATDRNGWTPLHCAAKAGHLEVV 1093
            .:     :|.      :|.||:||..||......||.:||.:||....|:|.|..|:..||...|
 Frog   629 CDVNIPSILM------KTPLHVAAETGHTSTARFLLSRGASVNAVTSEGFTALDLASNLGHYSAV 687

  Fly  1094 KLLCEAGASPK 1104
            |||.:..::.|
 Frog   688 KLLMDEQSNVK 698

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nompCNP_523483.2 ANKYR <125..371 CDD:440430 11/37 (30%)
ANK repeat 129..157 CDD:293786
ANK repeat 159..186 CDD:293786
ANK repeat 232..265 CDD:293786
ANK repeat 267..298 CDD:293786
ANKYR 281..572 CDD:440430 54/247 (22%)
ANK repeat 300..331 CDD:293786
ANK repeat 367..398 CDD:293786 7/30 (23%)
ANK repeat 400..431 CDD:293786 2/30 (7%)
ANK repeat 433..463 CDD:293786 7/32 (22%)
ANK repeat 469..499 CDD:293786 8/29 (28%)
ANK repeat 501..532 CDD:293786 5/32 (16%)
ANK repeat 534..575 CDD:293786 13/44 (30%)
ANK repeat 577..616 CDD:293786 7/40 (18%)
Ank_2 599..690 CDD:463710 11/92 (12%)
ANKYR 651..933 CDD:440430 54/283 (19%)
ANK repeat 660..690 CDD:293786 0/29 (0%)
ANK repeat 692..723 CDD:293786 7/30 (23%)
ANK repeat 725..757 CDD:293786 4/31 (13%)
ANK repeat 759..790 CDD:293786 11/30 (37%)
ANK repeat 792..824 CDD:293786 8/31 (26%)
ANKYR 843..1144 CDD:440430 75/270 (28%)
ANK repeat 861..893 CDD:293786 1/31 (3%)
ANK repeat 932..972 CDD:293786 12/40 (30%)
ANK repeat 974..1007 CDD:293786 12/32 (38%)
ANK repeat 1009..1041 CDD:293786 11/36 (31%)
TRPV 1035..1684 CDD:454755 25/75 (33%)
ANK repeat 1043..1074 CDD:293786 13/30 (43%)
ANK repeat 1076..1101 CDD:293786 10/24 (42%)
ANK repeat 1109..1134 CDD:293786
ripk4XP_002941332.1 STKc_RIP4_like 25..291 CDD:270927 45/219 (21%)
ANK repeat 441..469 CDD:293786 11/27 (41%)
ANKYR 442..701 CDD:440430 97/350 (28%)
ANK repeat 471..502 CDD:293786 8/33 (24%)
ANK repeat 504..535 CDD:293786 11/33 (33%)
ANK repeat 538..568 CDD:293786 13/29 (45%)
ANK repeat 570..602 CDD:293786 12/31 (39%)
ANK repeat 604..633 CDD:293786 10/28 (36%)
ANK repeat 637..668 CDD:293786 14/36 (39%)
ANK repeat 670..701 CDD:293786 11/29 (38%)
Blue background indicates that the domain is not in the aligned region.

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