| Sequence 1: | NP_523483.2 | Gene: | nompC / 33768 | FlyBaseID: | FBgn0016920 | Length: | 1761 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004612.2 | Gene: | TRPC6 / 7225 | HGNCID: | 12338 | Length: | 931 | Species: | Homo sapiens |
| Alignment Length: | 949 | Identity: | 206/949 - (21%) |
|---|---|---|---|
| Similarity: | 353/949 - (37%) | Gaps: | 293/949 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 946 RELLTSVPATVKSETPTGQSL----FGDLGTESGMTPLHLAAFSGNENVVRLLL---NSAGVQ-V 1002
Fly 1003 DAATIENGYNPLHLACFGGHMSVVGLLLSRSAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQG 1067
Fly 1068 A-------------------EINATDRNGW------TPLHCAAKAGHLEVVKLLCEAGASPKSET 1107
Fly 1108 NYGCAAIWFAASEGHNEVLRYLMNKEHDTYGLMEDKRFVYNLMVVSKNHNNKPIQEFV-LVSPA- 1170
Fly 1171 -------PVDTAAKLSNIYIVLSTKEKERAKDLVAAGKQCEAMATELLALAAGSDSAGKI----- 1223
Fly 1224 --LQATD--KRNVEFLDVLIENEQKEVIAHTVVQRYLQELWHGSLTWASWKILLLLVAFIVCPPV 1284
Fly 1285 WIGFTF-----------PMGHKFNKVPIIKFMSYLTSHIYLMIHLSIVGI------TPIYP---- 1328
Fly 1329 ------VLRLSLVPY-WYEVGLLIWLSGLL---------------LFELTNPSDKSGLGSIKVLV 1371
Fly 1372 LLLGMAGVGVHVSAFLFVSK-----------------------EYW-----------PTLVYCRN 1402
Fly 1403 QCFALAFLLACVQILDFLSFHHLFGPWAIIIGDLLKDLARFLAV-LAIFV------FGFSMHIVA 1460
Fly 1461 LNQSFANFSPEDLRSFEKKNRNRGYFSDDDMPTPRPPPVENYVDSRFSEFRRKHKDDLRMHPINS 1525
Fly 1526 FELLFFAVFGQTTTEQTQVDKIKNVATPTQPYWVEYLFKIVFGIYMLVSVVVLINLLIAMMSDTY 1590
Fly 1591 QRIQAQSDIEWKFGLSKL-IRNMHRTTTAPSPLNLV----TTWFM------WIVE---------K 1635
Fly 1636 VKARMKKKKRPSLVQMMGIRQASPRTKAGAKWLSKIKKDSVALSQ-VHLSPLGSQASFSQANQNR 1699
Fly 1700 IENVADWEAIAKKY--RALVGDEEGGSLKDSDAESGSQE 1736 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| nompC | NP_523483.2 | ANK repeat | 129..157 | CDD:293786 | |
| Ank_2 | 131..228 | CDD:289560 | |||
| ANK | 155..319 | CDD:238125 | |||
| ANK repeat | 159..186 | CDD:293786 | |||
| ANK repeat | 232..265 | CDD:293786 | |||
| Ank_2 | 237..331 | CDD:289560 | |||
| ANK | 263..387 | CDD:238125 | |||
| ANK repeat | 267..298 | CDD:293786 | |||
| ANK repeat | 300..331 | CDD:293786 | |||
| Ank_2 | 305..398 | CDD:289560 | |||
| ANK | 329..454 | CDD:238125 | |||
| ANK repeat | 367..398 | CDD:293786 | |||
| ANK repeat | 400..431 | CDD:293786 | |||
| Ank_2 | 405..498 | CDD:289560 | |||
| ANK | 428..555 | CDD:238125 | |||
| ANK repeat | 433..463 | CDD:293786 | |||
| ANK repeat | 469..499 | CDD:293786 | |||
| ANK | 496..641 | CDD:238125 | |||
| ANK repeat | 501..532 | CDD:293786 | |||
| Ank_2 | 507..616 | CDD:289560 | |||
| ANK repeat | 534..575 | CDD:293786 | |||
| ANK repeat | 577..616 | CDD:293786 | |||
| Ank_2 | 625..722 | CDD:289560 | |||
| ANK | 654..780 | CDD:238125 | |||
| ANK repeat | 660..690 | CDD:293786 | |||
| ANK repeat | 692..723 | CDD:293786 | |||
| Ank_2 | 697..790 | CDD:289560 | |||
| ANK | 720..847 | CDD:238125 | |||
| ANK repeat | 725..757 | CDD:293786 | |||
| ANK repeat | 759..790 | CDD:293786 | |||
| Ank_5 | 779..834 | CDD:290568 | |||
| ANK | 787..915 | CDD:238125 | |||
| ANK repeat | 792..824 | CDD:293786 | |||
| ANK repeat | 861..893 | CDD:293786 | |||
| Ank_4 | 865..915 | CDD:290365 | |||
| Ank_4 | 929..995 | CDD:290365 | 16/52 (31%) | ||
| ANK repeat | 932..972 | CDD:293786 | 9/29 (31%) | ||
| ANK | 969..1096 | CDD:238125 | 40/155 (26%) | ||
| ANK repeat | 974..1007 | CDD:293786 | 12/36 (33%) | ||
| Ank_2 | 979..1074 | CDD:289560 | 31/117 (26%) | ||
| ANK repeat | 1009..1041 | CDD:293786 | 9/31 (29%) | ||
| ANK | 1039..1159 | CDD:238125 | 27/144 (19%) | ||
| ANK repeat | 1043..1074 | CDD:293786 | 9/49 (18%) | ||
| Ank_2 | 1048..1135 | CDD:289560 | 22/111 (20%) | ||
| ANK repeat | 1076..1101 | CDD:293786 | 8/30 (27%) | ||
| ANK repeat | 1109..1134 | CDD:293786 | 3/24 (13%) | ||
| Ion_trans | <1393..1598 | CDD:278921 | 43/222 (19%) | ||
| TRPC6 | NP_004612.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..26 | ||
| trp | 82..897 | CDD:273311 | 204/944 (22%) | ||
| ANK 1 | 97..126 | 11/40 (28%) | |||
| ANK 2 | 132..161 | 9/37 (24%) | |||
| ANK repeat | 132..159 | CDD:293786 | 9/35 (26%) | ||
| ANK repeat | 161..185 | CDD:293786 | 7/24 (29%) | ||
| ANK 3 | 163..189 | 7/25 (28%) | |||
| ANK repeat | 212..247 | CDD:293786 | 10/34 (29%) | ||
| ANK 4 | 218..247 | 9/28 (32%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3609 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||