DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment nompC and Rnasel

DIOPT Version :9

Sequence 1:NP_523483.2 Gene:nompC / 33768 FlyBaseID:FBgn0016920 Length:1761 Species:Drosophila melanogaster
Sequence 2:XP_038946794.1 Gene:Rnasel / 359726 RGDID:727933 Length:743 Species:Rattus norvegicus


Alignment Length:566 Identity:139/566 - (24%)
Similarity:210/566 - (37%) Gaps:154/566 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   196 QTAVHLVSSRQTGTATNILRALLAAAGKDIRLKADGRGKIPLLLAVESGNQSMCRELLAAQTAEQ 260
            :|..|  |:.|.|:|        :|.|:    |..|:....|:.||..|:....::|| .|.|:.
  Rat     2 ETTDH--STPQCGSA--------SAGGQ----KTVGKDDYLLIEAVNKGDADRVQQLL-EQGADA 51

  Fly   261 LKATTANGDTALHLAARRRDVDMVRILVDYGTNVDTQNGEGQTPLHIAAAEGDEALLKYF----- 320
            .....:.|.|.||.|.:...||:|.:|:.||.:...:...|.||..||...||.:||:.|     
  Rat    52 NVCEESGGWTPLHNAVQSGRVDIVNLLLRYGADPHRRKKNGATPFIIAGICGDVSLLQIFLSRGA 116

  Fly   321 -------YGVRASASIAD-----------------------NQDR--------TPMHLAAENGHA 347
                   :|..|....|:                       .:||        |.:..||||||.
  Rat   117 NINERDMHGFTAFMEAAEYGNVEALKFLFAEGADVNLRRETTEDRRRLKQGGATALMSAAENGHP 181

  Fly   348 HVIEILADKFKASIFERTKDGSTLMHIASLNGHA--------ECATMLFKKGVYLHMPNKDGARS 404
            .|:.||.|:.||....|...|...:..:.||...        |..::|.:.|..:::..:.....
  Rat   182 EVVRILLDEMKAEADARDNMGRNALIRSLLNRDCENVEIHVEEITSVLIQYGADINVRGEGEKTP 246

  Fly   405 IHTAAAYGHTGIINTLL-QKGEKVDVTTNDNYTALHIAVESAKPAVVETLLGFGADVHVRGGKLR 468
            :.:|....|||::..|| |:|.||:...::..|||.||||.....:|..||..|||  .:.|.| 
  Rat   247 LISAVERKHTGLVQMLLSQEGIKVNDRDSEGKTALQIAVELKLKEIVRLLLEKGAD--TKCGDL- 308

  Fly   469 ETPLHIAARVKDGDRCALML-LKSGASPNLTTDDC----------LTPVHVAARH--GNLATLMQ 520
               :.||.|..|.....|:| .::....|....|.          |..:|..:|.  |.|...| 
  Rat   309 ---VWIAKRNYDHGLVKLLLSYEANHDTNPPAKDWLPHSARWGEDLKRLHSVSRPMIGKLKIFM- 369

  Fly   521 LLEDEGDPLYK-SNTGETPLHMA------------CR---------ACHPDIVRH---LIETVKE 560
                  :..|| ::|.|..:::.            |.         ||..|...|   |.....|
  Rat   370 ------NDAYKIASTSEGGIYLGIYDNREVAVKVFCENSSRGRKEVACLRDCGDHSNLLTFYGSE 428

  Fly   561 KHGPDKATTYINSVNEDGATALHYTCQITKEE-VKIPESDKQIVRMLLENGADVTLQTKTALETA 624
            :|   |...|:       ..:|   |:.|.|: :.:|..:.      :|.|.|     |.||...
  Rat   429 EH---KGNLYV-------CVSL---CESTLEKFLNVPREEP------MEKGED-----KFALSVL 469

  Fly   625 FHYCAVAGNNDVLMEMISHMN---PT---DIQKAM---NRQSSVGW 661
            .  ....|...:.|...||.|   |.   |.:||:   :...|:.|
  Rat   470 L--SIFKGVQKLHMHGYSHQNLQPPNILIDSEKAVRLADFDESIQW 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nompCNP_523483.2 ANK repeat 129..157 CDD:293786
Ank_2 131..228 CDD:289560 8/31 (26%)
ANK 155..319 CDD:238125 38/122 (31%)
ANK repeat 159..186 CDD:293786
ANK repeat 232..265 CDD:293786 8/32 (25%)
Ank_2 237..331 CDD:289560 31/105 (30%)
ANK 263..387 CDD:238125 44/174 (25%)
ANK repeat 267..298 CDD:293786 11/30 (37%)
ANK repeat 300..331 CDD:293786 12/42 (29%)
Ank_2 305..398 CDD:289560 32/143 (22%)
ANK 329..454 CDD:238125 41/164 (25%)
ANK repeat 367..398 CDD:293786 6/38 (16%)
ANK repeat 400..431 CDD:293786 10/31 (32%)
Ank_2 405..498 CDD:289560 32/94 (34%)
ANK 428..555 CDD:238125 38/164 (23%)
ANK repeat 433..463 CDD:293786 13/29 (45%)
ANK repeat 469..499 CDD:293786 7/30 (23%)
ANK 496..641 CDD:238125 35/182 (19%)
ANK repeat 501..532 CDD:293786 9/43 (21%)
Ank_2 507..616 CDD:289560 27/136 (20%)
ANK repeat 534..575 CDD:293786 12/64 (19%)
ANK repeat 577..616 CDD:293786 8/39 (21%)
Ank_2 625..722 CDD:289560 11/46 (24%)
ANK 654..780 CDD:238125 2/8 (25%)
ANK repeat 660..690 CDD:293786 1/2 (50%)
ANK repeat 692..723 CDD:293786
Ank_2 697..790 CDD:289560
ANK 720..847 CDD:238125
ANK repeat 725..757 CDD:293786
ANK repeat 759..790 CDD:293786
Ank_5 779..834 CDD:290568
ANK 787..915 CDD:238125
ANK repeat 792..824 CDD:293786
ANK repeat 861..893 CDD:293786
Ank_4 865..915 CDD:290365
Ank_4 929..995 CDD:290365
ANK repeat 932..972 CDD:293786
ANK 969..1096 CDD:238125
ANK repeat 974..1007 CDD:293786
Ank_2 979..1074 CDD:289560
ANK repeat 1009..1041 CDD:293786
ANK 1039..1159 CDD:238125
ANK repeat 1043..1074 CDD:293786
Ank_2 1048..1135 CDD:289560
ANK repeat 1076..1101 CDD:293786
ANK repeat 1109..1134 CDD:293786
Ion_trans <1393..1598 CDD:278921
RnaselXP_038946794.1 PHA02875 29..>188 CDD:165206 43/159 (27%)
ANK repeat 29..55 CDD:293786 8/26 (31%)
ANK repeat 59..89 CDD:293786 11/29 (38%)
ANK repeat 91..122 CDD:293786 10/30 (33%)
ANK repeat 124..153 CDD:293786 3/28 (11%)
ANK repeat 167..199 CDD:293786 13/31 (42%)
Ank_4 170..216 CDD:372654 17/45 (38%)
ANK repeat 201..239 CDD:293786 6/37 (16%)
Ank_2 224..302 CDD:403870 24/77 (31%)
ANK repeat 242..274 CDD:293786 10/31 (32%)
PTZ00322 259..>369 CDD:140343 34/115 (30%)
ANK repeat 276..301 CDD:293786 10/24 (42%)
PKc_like 379..590 CDD:419665 33/161 (20%)
RNase_RNase-L 599..715 CDD:199218
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.