Protein Alignment nompC and Trpc7

DIOPT Version :9

• Sequence 1: NP_523483.2
• Gene: nompC / 33768
• FlyBaseID: FBgn0016920
• Length: 1761
• Species: Drosophila melanogaster
• Sequence 2: XP_017455952.1
• Gene: Trpc7 / 282822
• RGDID: 628820
• Length: 904
• Species: Rattus norvegicus
• Alignment Length: 877
• Identity: 183/877 - (20%)
• Similarity: 324/877 - (36%)
• Gaps: 254/877 - (28%)

  Fly   966 LFGDLGTESGMTP-----LHLAAFSGNENVVRLLLNSAGVQVDAATIENGYNPLHLACFGGHMSV 1025
            :|.:.||  .:||     |..|.: ||..|||.:|..:...........|.|.|.||....|:.|
  Rat   129 MFNEKGT--SLTPEEERFLDSAEY-GNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEV 190

  Fly  1026 VGLLLSRSAELLQSQDRNGRTG--LHIAAMHGHIQMVEILL-----GQGAEIN------------ 1071
                    .|||..::...|.|  |.:|...|::::||.:|     .||..:.
  Rat   191 --------TELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQELRDDD 247

  Fly  1072 --ATDRNGW------TPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAASEGHNEVLRY 1128
              |.|.:|.      ||:..||.....|:|.:|...||..:...:|.|..         ||...
  Rat   248 FYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKC---------NECTE- 302

  Fly  1129 LMNKEHDTYGLMEDKRFVYNLMVVSKNHNNKPIQEFVLVSPAPVDTAAKLSNIYIVLSTKEKERA 1193
              .:..|::.....:...|..:..:        ....|.|..||.||.:|||....|:..|.|..
  Rat   303 --KQRKDSFSHSRSRMNAYKGLASA--------AYLSLSSEDPVLTALELSNELARLANIETEFK 357

  Fly  1194 KDLVAAGKQCEAMATELLALAAGSDSAGKILQATDKRNVEFLDVLIENEQKEVIAHTVVQRYLQE 1258
            .|......||:...                        |..||:..:.|:.|.|.:..|.  ||
  Rat   358 NDYRKLSMQCKDFV------------------------VGVLDLCRDTEEVEAILNGDVN--LQ- 395

  Fly  1259 LWHGSLTWA-----SWKILLLLVAFIVCPPVWIGFTFPMGHKFNKVPIIKFMSYLTSHIYLMIHL 1318
                  .|:     |...:.|.:.:.|..   :|.|.       :.|.:||:::..| ..:.:.|
  Rat   396 ------VWSDHHRPSLSRIKLAIKYEVKK---LGRTL-------RSPFMKFVAHAVS-FTIFLGL 443

  Fly  1319 SIV-------GITPI-------YP--VLRLSLVPY-WYEVGLLIWLSGLL--------------- 1351
            .:|       |:..:       ||  :.|:....: |.|:.::.|:.|::
  Rat   444 LVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREY 508

  Fly  1352 LFELTNPSDKSGLGSIKVLV--------------------------LLLGMAGVGVHVSAFLFVS 1390
            :..|.|..|   .|.:.|.|                          :.|....:...|:.|.:..
  Rat   509 VLHLWNLLD---FGMLSVFVASFTARFMAFLKASEAQLYVDQYVQDVTLHNVSLPPEVAYFTYAR 570

  Fly  1391 KEYWPTLVYCRNQ-CFALAFLLACVQILDFLSFHHLFGPWAIIIGDLLKDLARFLAVLAIFVFGF 1454
            .::||:.....:: .:|:|.:|:..:|...|..:..|||..|.:|..:||:.:|   :.||:..|
  Rat   571 DKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKF---MVIFIMVF 632

  Fly  1455 SMHIVALNQSFANFSPEDLRSFEKKNRNRGYFSDDDMPTPRPPPVENYVDSRFSEFRRKHKDDLR 1519
            ...::.:...::.:            |...|       .|....||
  Rat   633 VAFMIGMFNLYSYY------------RGAKY-------NPAFTTVE------------------- 659

  Fly  1520 MHPINSFELLFFAVFGQTTTEQTQVDKIKNVATPTQPYWVEYLFKIVFGIYMLVSVVVLINLLIA 1584
                .||:.||:::||        :.::.:|.......::|.:..:::|:|.:..||||:|:|||
  Rat   660 ----ESFKTLFWSIFG--------LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIA 712

  Fly  1585 MMSDTYQRIQAQSDIEWKFGLSKL-IRNMHRTTTAPSPLNLVTT--WFMWIVEKVKARM-----K 1641
            |::::||.|:..:|:||||..:|| :.......|.|:|.|||.:  .|.:::.::|..:     .
  Rat   713 MINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKS 777

  Fly  1642 KKKRPSLVQMMGIRQASPRTKAGAKWLSKIKKDSVALSQVHLSPLGSQASFSQANQNRIENVADW 1706
            |.||......||:..            ||.:|........:...|.:.::||:  ..|.:.:  .
  Rat   778 KAKRCENDLEMGMLN------------SKFRKTRYQAGMRNSENLTANSTFSK--PTRYQKI--M 826

  Fly  1707 EAIAKKY--RALVGDEEGGSLKDSDAESGSQE 1736
            :.:.|:|  :|.| |.|...:.:.:.:...|:
  Rat   827 KRLIKRYVLKAQV-DRENDEVNEGELKEIKQD 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nompC	NP_523483.2	ANK repeat	129..157	CDD:293786
		Ank_2	131..228	CDD:289560
		ANK	155..319	CDD:238125
		ANK repeat	159..186	CDD:293786
		ANK repeat	232..265	CDD:293786
		Ank_2	237..331	CDD:289560
		ANK	263..387	CDD:238125
		ANK repeat	267..298	CDD:293786
		ANK repeat	300..331	CDD:293786
		Ank_2	305..398	CDD:289560
		ANK	329..454	CDD:238125
		ANK repeat	367..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		Ank_2	405..498	CDD:289560
		ANK	428..555	CDD:238125
		ANK repeat	433..463	CDD:293786
		ANK repeat	469..499	CDD:293786
		ANK	496..641	CDD:238125
		ANK repeat	501..532	CDD:293786
		Ank_2	507..616	CDD:289560
		ANK repeat	534..575	CDD:293786
		ANK repeat	577..616	CDD:293786
		Ank_2	625..722	CDD:289560
		ANK	654..780	CDD:238125
		ANK repeat	660..690	CDD:293786
		ANK repeat	692..723	CDD:293786
		Ank_2	697..790	CDD:289560
		ANK	720..847	CDD:238125
		ANK repeat	725..757	CDD:293786
		ANK repeat	759..790	CDD:293786
		Ank_5	779..834	CDD:290568
		ANK	787..915	CDD:238125
		ANK repeat	792..824	CDD:293786
		ANK repeat	861..893	CDD:293786
		Ank_4	865..915	CDD:290365
		Ank_4	929..995	CDD:290365	12/33 (36%)
		ANK repeat	932..972	CDD:293786	1/5 (20%)
		ANK	969..1096	CDD:238125	41/158 (26%)
		ANK repeat	974..1007	CDD:293786	10/37 (27%)
		Ank_2	979..1074	CDD:289560	29/115 (25%)
		ANK repeat	1009..1041	CDD:293786	10/31 (32%)
		ANK	1039..1159	CDD:238125	28/146 (19%)
		ANK repeat	1043..1074	CDD:293786	11/51 (22%)
		Ank_2	1048..1135	CDD:289560	24/111 (22%)
		ANK repeat	1076..1101	CDD:293786	8/30 (27%)
		ANK repeat	1109..1134	CDD:293786	4/24 (17%)
		Ion_trans	<1393..1598	CDD:278921	45/205 (22%)
Trpc7	XP_017455952.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3609
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810