DRSC/TRiP Functional Genomics Resources

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Protein Alignment nompC and ANKK1

DIOPT Version :9

Sequence 1:NP_523483.2 Gene:nompC / 33768 FlyBaseID:FBgn0016920 Length:1761 Species:Drosophila melanogaster
Sequence 2:XP_011541038.1 Gene:ANKK1 / 255239 HGNCID:21027 Length:776 Species:Homo sapiens


Alignment Length:535 Identity:150/535 - (28%)
Similarity:231/535 - (43%) Gaps:78/535 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   612 DVTLQTKTALETAFHYCAVAGNNDVLMEMISHMNPTDIQKAMNRQSSVGWTPLLIACHRGHMEL- 675
            |:|::|                 |:|:.::.........||:.|:         ::|   .:.| 
Human   290 DITIET-----------------DILLSLLQSRVAVPESKALARK---------VSC---KLSLR 325

  Fly   676 ----VNNLLANHARVDVFDTEG--RSALHLAAERGYL----HVCDALLTNKAFINSKSRVGRTAL 730
                ||..::... :|..|:..  :.||.|:..:..:    .:|  :..||.          |.|
Human   326 QPGEVNEDISQEL-MDSADSGNYLKRALQLSDRKNLVPRDEELC--IYENKV----------TPL 377

  Fly   731 HLAAMNGFTHLVKFLIKDHNAVIDILTLRKQTPLHLAAASGQMEVCQLLLELGANIDATDDLGQK 795
            |.....|....|:.|:. |...:|..|....|||.:||...|.::|.|||..||:.:..|:.|..
Human   378 HFLVAQGSVEQVRLLLA-HEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWA 441

  Fly   796 PIHVAAQNNYSEVAKLFLQQHPSLVNATSKDGNTCAHIAAMQGSVKVIEELMKFDRS-GVISARN 859
            |:|.||||.....|:|.| .|.:.|:|..::|.|..|:||......|...|:..... .:..|..
Human   442 PLHFAAQNGDDGTARLLL-DHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEG 505

  Fly   860 KLTDATPLQLAAEGGHADVVKALVRAGASCTEENKAGFTAVHLAAQNGHGQVLDVLKSTNSLRIN 924
            |    |||.:||..||..:||.|...||....:.:...|.:|||.:.|..:.:..|..:.::...
Human   506 K----TPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDA 566

  Fly   925 SKKLGLTPLHVAAYYGQADTVRELLTSVPATVKSETPTGQSLFGDLGTESGMTPLHLAAFSGNEN 989
            ..:.|..|||.||..|:....:.||.           .|.||  :|.|..|.|||||||:.|:..
Human   567 LDQSGYGPLHTAAARGKYLICKMLLR-----------YGASL--ELPTHQGWTPLHLAAYKGHLE 618

  Fly   990 VVRLLLNS-AGVQVDAATIENGYNPLHLACFGGHMSVVGLLLSRSAELLQSQDRNGRTGLHIAAM 1053
            ::.||..| |.:....|.   .:.|||||...|..:||..||...|: ..:.:::|.|.||:|..
Human   619 IIHLLAESHANMGALGAV---NWTPLHLAARHGEEAVVSALLQCGAD-PNAAEQSGWTPLHLAVQ 679

  Fly  1054 HGHIQMVEILLGQGAEINATDRNGWTPLHCAAKAGHLEVVKLLCEAGASPKSETNYGCAAIWFAA 1118
            ......|..||...|.::|.::.||||.|.||..|:..::|:|.||||....:....|..:..|.
Human   680 RSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 744

  Fly  1119 SEGHNEVLRYLMNKE 1133
            ......::.:|..||
Human   745 RSRKQGIMSFLEGKE 759

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
nompCNP_523483.2 ANK repeat 129..157 CDD:293786
Ank_2 131..228 CDD:289560
ANK 155..319 CDD:238125
ANK repeat 159..186 CDD:293786
ANK repeat 232..265 CDD:293786
Ank_2 237..331 CDD:289560
ANK 263..387 CDD:238125
ANK repeat 267..298 CDD:293786
ANK repeat 300..331 CDD:293786
Ank_2 305..398 CDD:289560
ANK 329..454 CDD:238125
ANK repeat 367..398 CDD:293786
ANK repeat 400..431 CDD:293786
Ank_2 405..498 CDD:289560
ANK 428..555 CDD:238125
ANK repeat 433..463 CDD:293786
ANK repeat 469..499 CDD:293786
ANK 496..641 CDD:238125 5/28 (18%)
ANK repeat 501..532 CDD:293786
Ank_2 507..616 CDD:289560 2/3 (67%)
ANK repeat 534..575 CDD:293786
ANK repeat 577..616 CDD:293786 2/3 (67%)
Ank_2 625..722 CDD:289560 17/107 (16%)
ANK 654..780 CDD:238125 30/136 (22%)
ANK repeat 660..690 CDD:293786 5/34 (15%)
ANK repeat 692..723 CDD:293786 6/36 (17%)
Ank_2 697..790 CDD:289560 26/96 (27%)
ANK 720..847 CDD:238125 41/126 (33%)
ANK repeat 725..757 CDD:293786 8/31 (26%)
ANK repeat 759..790 CDD:293786 12/30 (40%)
Ank_5 779..834 CDD:290568 21/54 (39%)
ANK 787..915 CDD:238125 40/128 (31%)
ANK repeat 792..824 CDD:293786 13/31 (42%)
ANK repeat 861..893 CDD:293786 12/31 (39%)
Ank_4 865..915 CDD:290365 17/49 (35%)
Ank_4 929..995 CDD:290365 24/65 (37%)
ANK repeat 932..972 CDD:293786 12/39 (31%)
ANK 969..1096 CDD:238125 46/127 (36%)
ANK repeat 974..1007 CDD:293786 14/33 (42%)
Ank_2 979..1074 CDD:289560 32/95 (34%)
ANK repeat 1009..1041 CDD:293786 11/31 (35%)
ANK 1039..1159 CDD:238125 29/95 (31%)
ANK repeat 1043..1074 CDD:293786 10/30 (33%)
Ank_2 1048..1135 CDD:289560 27/86 (31%)
ANK repeat 1076..1101 CDD:293786 12/24 (50%)
ANK repeat 1109..1134 CDD:293786 5/25 (20%)
Ion_trans <1393..1598 CDD:278921
ANKK1XP_011541038.1 STKc_RIP4_like 25..303 CDD:270927 5/29 (17%)