DRSC/TRiP Functional Genomics Resources

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Protein Alignment nompC and ANKRD60

DIOPT Version :9

Sequence 1:NP_523483.2 Gene:nompC / 33768 FlyBaseID:FBgn0016920 Length:1761 Species:Drosophila melanogaster
Sequence 2:NP_001291298.1 Gene:ANKRD60 / 140731 HGNCID:16217 Length:345 Species:Homo sapiens


Alignment Length:264 Identity:66/264 - (25%)
Similarity:93/264 - (35%) Gaps:65/264 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   884 RAGASCTEENKAG------FTAVHLAAQNGHGQVL-----------DVLKSTNSLRINSKKLGLT 931
            ||||......:.|      ..|..||...|..|.|           |:......||:..::.| .
Human    42 RAGAQGCGGPRVGSAD
SRALPAQPLACARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETG-E 105

  Fly   932 PLHVAAYYGQADTVRE------LLTSVPATVKSETPTGQSLFGDLGT------------------ 972
            ...||...|.. ||||      |:..:|..::......:.:..|..|                  
Human   106 MFRVANCRGDM-TVRELKEELDLMVGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWH 169

  Fly   973 ESGMTPLHLAAFSGNENVVRLLLNSAGVQVDAA-----------------TIENGYNPLHLACFG 1020
            ..|.|.|.|||..|:.:    .|:..|:..|:.                 |.:..:..|::|...
Human   170 HDGWTELVLAAVEGDPS----KLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHR 230

  Fly  1021 GHMSVVGLLLSRSAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQGAEINATDRNGWTPLHCAA 1085
            ||...|..||...|..| |:...|||.||:||..|....:.:||..||.|:..|..|.||:..|.
Human   231 GHFDAVQYLLEHGASCL-SRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAH 294

  Fly  1086 KAGH 1089
            :..|
Human   295 RLNH 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nompCNP_523483.2 ANK repeat 129..157 CDD:293786
Ank_2 131..228 CDD:289560
ANK 155..319 CDD:238125
ANK repeat 159..186 CDD:293786
ANK repeat 232..265 CDD:293786
Ank_2 237..331 CDD:289560
ANK 263..387 CDD:238125
ANK repeat 267..298 CDD:293786
ANK repeat 300..331 CDD:293786
Ank_2 305..398 CDD:289560
ANK 329..454 CDD:238125
ANK repeat 367..398 CDD:293786
ANK repeat 400..431 CDD:293786
Ank_2 405..498 CDD:289560
ANK 428..555 CDD:238125
ANK repeat 433..463 CDD:293786
ANK repeat 469..499 CDD:293786
ANK 496..641 CDD:238125
ANK repeat 501..532 CDD:293786
Ank_2 507..616 CDD:289560
ANK repeat 534..575 CDD:293786
ANK repeat 577..616 CDD:293786
Ank_2 625..722 CDD:289560
ANK 654..780 CDD:238125
ANK repeat 660..690 CDD:293786
ANK repeat 692..723 CDD:293786
Ank_2 697..790 CDD:289560
ANK 720..847 CDD:238125
ANK repeat 725..757 CDD:293786
ANK repeat 759..790 CDD:293786
Ank_5 779..834 CDD:290568
ANK 787..915 CDD:238125 12/47 (26%)
ANK repeat 792..824 CDD:293786
ANK repeat 861..893 CDD:293786 4/8 (50%)
Ank_4 865..915 CDD:290365 12/47 (26%)
Ank_4 929..995 CDD:290365 19/89 (21%)
ANK repeat 932..972 CDD:293786 10/45 (22%)
ANK 969..1096 CDD:238125 42/156 (27%)
ANK repeat 974..1007 CDD:293786 10/49 (20%)
Ank_2 979..1074 CDD:289560 32/111 (29%)
ANK repeat 1009..1041 CDD:293786 10/31 (32%)
ANK 1039..1159 CDD:238125 20/51 (39%)
ANK repeat 1043..1074 CDD:293786 13/30 (43%)
Ank_2 1048..1135 CDD:289560 16/42 (38%)
ANK repeat 1076..1101 CDD:293786 5/14 (36%)
ANK repeat 1109..1134 CDD:293786
Ion_trans <1393..1598 CDD:278921
ANKRD60NP_001291298.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..57 5/14 (36%)
UBL 103..163 CDD:176364 12/61 (20%)
ANK 171..298 CDD:238125 39/131 (30%)
Ank_5 214..260 CDD:290568 16/46 (35%)
ANK 1 219..249 9/30 (30%)
ANK repeat 223..250 CDD:293786 10/27 (37%)
Ank_5 239..293 CDD:290568 22/54 (41%)
ANK repeat 252..283 CDD:293786 13/30 (43%)
ANK 2 252..281 13/28 (46%)
ANK repeat 285..318 CDD:293786 5/14 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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