DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nompC and ankdd1a

DIOPT Version :9

Sequence 1:	NP_523483.2	Gene:	nompC / 33768	FlyBaseID:	FBgn0016920	Length:	1761	Species:	Drosophila melanogaster
Sequence 2:	XP_002938399.3	Gene:	ankdd1a / 100489003	XenbaseID:	XB-GENE-6045405	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	117/404 - (28%)
Similarity:	190/404 - (47%)	Gaps:	51/404 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 VCDALLTNKAFINSKSRVGRTALHLAAMNGFTHLVKFLIKDHNAVIDILTLRK--QTPLHLAAAS 770
            |||    ::..:.|:     ...|.||....|..::.||:   ..:|:.....  :|.||.||.:
Frog     6 VCD----DEILLRSE-----RDFHNAAKTNDTEKMRQLIE---LGVDVRVKNSVDRTALHWAAGA 58

  Fly   771 GQMEVCQLLLELGANIDATDDLGQKPIHVAAQNNYSEVAKLFLQQHPSLVNATSKDGNTCAHIAA 835
            |..:..|||||..|.:|..|..|...:.:.|...:..:.:: |....:.:|..:|:|....|.||
Frog    59 GHKQAVQLLLEHDAPMDKEDSFGMNALLLGAWFGHLPILQI-LVNAGAKINCQNKNGLNLLHCAA 122

  Fly   836 MQGSVKVIEELM---------KFDRSGVISARNKLTDATPLQLAAEGGHADVVKALVRAGASCTE 891
            ::|.:||:|.:|         |.|:||          .|...||||.|..:.|:.|:.:|...:.
Frog   123 LRGHIKVMEFIMEDLEGIRLDKVDKSG----------KTAFHLAAEHGQLEAVEFLIGSGCQHSL 177

  Fly   892 ENKAGFTAVHLAAQNGHGQVLDVLKSTNSLRINSKKL-GLTPLHVAAYYGQADTVRELLTSVPAT 955
            ::|...||:|||.:|||.:||..:..| .:.:|.|.. |:|.||:|...|..|.|| :|......
Frog   178 KDKDKNTALHLATKNGHVEVLQKIVET-GVELNEKNTEGMTALHLATEGGYFDCVR-ILLDAGCD 240

  Fly   956 VKSETPTGQSLFGDLGTESGMTPLHLAAFSGNENVVRLLLNSAGVQVDAATIENGYNPLHLACFG 1020
            |.::|           .:..|..||.:||.|.|::.|:|:: ||:.::|...... ..||::...
Frog   241 VNAQT-----------EQKSMNGLHYSAFHGYEDIARILID-AGININAVNHRKS-TALHISILQ 292

  Fly  1021 GHMSVVGLLLSRSAELLQSQDRNGRTGLHIAAMHGHIQMVEILLGQGAEINATDRNGWTPLHCAA 1085
            ...:.|.||:....: |...|...:|.|||||.||...|.|::|..|..:...|:.|.|.|..||
Frog   293 NFPATVKLLIDFECD-LDIPDYRLQTPLHIAAEHGRQDMAEMILIAGVNLKLQDKQGKTSLDVAA 356

  Fly  1086 KAGHLEVVKLLCEA 1099
            :..|:.:..::.:|
Frog   357 RGNHINLADMIIKA 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nompC	NP_523483.2	ANK repeat	129..157	CDD:293786
		Ank_2	131..228	CDD:289560
		ANK	155..319	CDD:238125
		ANK repeat	159..186	CDD:293786
		ANK repeat	232..265	CDD:293786
		Ank_2	237..331	CDD:289560
		ANK	263..387	CDD:238125
		ANK repeat	267..298	CDD:293786
		ANK repeat	300..331	CDD:293786
		Ank_2	305..398	CDD:289560
		ANK	329..454	CDD:238125
		ANK repeat	367..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		Ank_2	405..498	CDD:289560
		ANK	428..555	CDD:238125
		ANK repeat	433..463	CDD:293786
		ANK repeat	469..499	CDD:293786
		ANK	496..641	CDD:238125
		ANK repeat	501..532	CDD:293786
		Ank_2	507..616	CDD:289560
		ANK repeat	534..575	CDD:293786
		ANK repeat	577..616	CDD:293786
		Ank_2	625..722	CDD:289560	3/13 (23%)
		ANK	654..780	CDD:238125	19/73 (26%)
		ANK repeat	660..690	CDD:293786
		ANK repeat	692..723	CDD:293786	4/14 (29%)
		Ank_2	697..790	CDD:289560	24/83 (29%)
		ANK	720..847	CDD:238125	35/128 (27%)
		ANK repeat	725..757	CDD:293786	7/31 (23%)
		ANK repeat	759..790	CDD:293786	13/32 (41%)
		Ank_5	779..834	CDD:290568	13/54 (24%)
		ANK	787..915	CDD:238125	40/136 (29%)
		ANK repeat	792..824	CDD:293786	4/31 (13%)
		ANK repeat	861..893	CDD:293786	9/31 (29%)
		Ank_4	865..915	CDD:290365	20/49 (41%)
		Ank_4	929..995	CDD:290365	20/65 (31%)
		ANK repeat	932..972	CDD:293786	10/39 (26%)
		ANK	969..1096	CDD:238125	38/126 (30%)
		ANK repeat	974..1007	CDD:293786	12/32 (38%)
		Ank_2	979..1074	CDD:289560	30/94 (32%)
		ANK repeat	1009..1041	CDD:293786	6/31 (19%)
		ANK	1039..1159	CDD:238125	21/61 (34%)
		ANK repeat	1043..1074	CDD:293786	12/30 (40%)
		Ank_2	1048..1135	CDD:289560	19/52 (37%)
		ANK repeat	1076..1101	CDD:293786	7/24 (29%)
		ANK repeat	1109..1134	CDD:293786
		Ion_trans	<1393..1598	CDD:278921
ankdd1a	XP_002938399.3	Ank_2	19..111	CDD:403870	25/95 (26%)
		ANK repeat	19..45	CDD:293786	7/28 (25%)
		ANK repeat	47..78	CDD:293786	13/30 (43%)
		ANK repeat	80..111	CDD:293786	4/31 (13%)
		PHA03095	100..>369	CDD:222980	89/294 (30%)
		ANK repeat	113..146	CDD:293786	10/32 (31%)
		ANK repeat	148..179	CDD:293786	11/40 (28%)
		ANK repeat	181..212	CDD:293786	12/31 (39%)
		ANK repeat	214..244	CDD:293786	11/30 (37%)
		ANK repeat	251..279	CDD:293786	11/28 (39%)
		ANK repeat	281..312	CDD:293786	6/32 (19%)
		ANK repeat	314..345	CDD:293786	12/30 (40%)
		DD	421..496	CDD:417479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910