DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12512 and aas

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_417313.1	Gene:	aas / 947315	ECOCYCID:	EG11679	Length:	719	Species:	Escherichia coli

Alignment Length:	552	Identity:	120/552 - (21%)
Similarity:	213/552 - (38%)	Gaps:	83/552 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TIGQQLELSASNFGDVEAIVSCHEGKRY---SFKSLLQEADALAAGFRKLGLQPGDAVGLWAPNY 109
            |:.:.|..:...||   |...|.|...:   |::.||.:...:.....|..:: |:.:||..||
E. coli   205 TLYESLLSAMYRFG---AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVE-GERIGLMLPN- 264

  Fly   110 LHWYLGMMGAARAGLTSVGLNPAYQG-----PEIAYCLNKVNVKAIIAPETFKTQNYYEILRDIC 169
                .|:..|...|..:....||...     ..:...:....:|.|.....|
E. coli   265 ----AGISAAVIFGAIARRRMPAMMNYTAGVKGLTSAITAAEIKTIFTSRQF------------- 312

  Fly   170 PEISDADTGKI--RSEKFPHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESA 232
                 .|.||:  ..|:...:|.|.:   :.||..:...|.:.:.:......:|::::.  ||..
E. coli   313 -----LDKGKLWHLPEQLTQVRWVYL---EDLKADVTTADKVWIFAHLLMPRLAQVKQQ--PEEE 367

  Fly   233 CNIQFTSGTTGNPKAACLTHHNFVNNGIHVGNRNEL-EGERICVQVPMFHAFGVIISIMAALTKG 296
            ..|.||||:.|:||....:|.:.:.|...:....:. ..:|....:|:||:||:.:.:...|..|
E. coli   368 ALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTG 432

  Fly   297 ATMVLPAAGFSPKDSLQAIVNEKCSVIHGTPTM---YVDLVNTQKKLQVPLGRIKKAVTGGAIV- 357
            |.:.|..:....:...:.:.:..|:|:.||.|.   |....|     .....|::..|.|...:
E. coli   433 AEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFAN-----PYDFYRLRYVVAGAEKLQ 492

  Fly   358 --SPQLIKDVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVDAEGR 420
              :.||.:|...:..:|.    ||:||...|:..::|..:..   .:||.:...::|:::...|
E. coli   493 ESTKQLWQDKFGLRILEG----YGVTECAPVVSINVPMAAKP---GTVGRILPGMDARLLSVPG- 549

  Fly   421 CVPFGQPGELCVRGYTTMLGYHDDEE------KTKETIGNDR---WLRTGDQFVLEANGYGRIVG 476
               ..:.|.|.::|...|.||...|:      .|.|.:..:.   |..|||....:..|:.:|.|
E. coli   550 ---IEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQG 611

  Fly   477 RLKEMLIRGGENIFPKEIEDF-LNAHPQVIEAHVIGVPDERLGEEVCAYVRLEEGVDPASFTAET 540
            |.|......||.:..:.:|.. |...|..:.|..| ..|...||.:..:....|      .|.:.
E. coli   612 RAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAI-KSDASKGEALVLFTTDNE------LTRDK 669

  Fly   541 LKAYAKGK-LAHFKVPRYVIPIDAFPKTTSGK 571
            |:.||:.. :....|||.:..:...|...|||
E. coli   670 LQQYAREHGVPELAVPRDIRYLKQMPLLGSGK 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	120/552 (22%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	86/361 (24%)
aas	NP_417313.1	PRK08043	1..718	CDD:181207	120/552 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	0.900