Protein Alignment CG12512 and prpE

DIOPT Version :9

• Sequence 1: NP_608924.1
• Gene: CG12512 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_414869.1
• Gene: prpE / 946891
• ECOCYCID: G6200
• Length: 628
• Species: Escherichia coli
• Alignment Length: 595
• Identity: 140/595 - (23%)
• Similarity: 232/595 - (38%)
• Gaps: 112/595 - (18%)

  Fly    40 GKDPLVYRTIGQQLELSASNFGDVEAIVSCHEGKRYSFKSLLQEADALAAGFRKLGLQPGDAVGL 104
            |:..|.:..|.:.||........:.......|.:.::|:.|..|.:|:|:..|.||:|.||.|.:
E. coli    49 GRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRSLGVQRGDRVLV 113

  Fly   105 WAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPET----FKTQNYYEIL 165
            :.|.....::.::..||.|.....:...:....:|..::......|::.:.    .|...|.::|
E. coli   114 YMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIVSADAGARGGKIIPYKKLL 178

  Fly   166 RDICPEISDADTGKIRSEKFPHLRSVIIDSNDSLKGAL---RFDDFLDLASK--SEREEVAKMQK 225
            .|   .||.|       :..|  |.|::......|.|.   |..||..|..:  ..|..||.::.
E. coli   179 DD---AISQA-------QHQP--RHVLLVDRGLAKMARVSGRDVDFASLRHQHIGARVPVAWLES 231

  Fly   226 SILPESACNIQFTSGTTGNPKAACLTHHNFVNNGIHVGNRNELEGERICVQVPMFHAFG------ 284
            :   |::| |.:||||||.||                |.:.::.|..:.:...|...||
E. coli   232 N---ETSC-ILYTSGTTGKPK----------------GVQRDVGGYAVALATSMDTIFGGKAGSV 276

  Fly   285 ----------------VIISIMAALTKGATMVLPAAGFSPKDSLQAIVNEKCSV--IHGTPTMYV 331
                            |...::|.:   ||:|.......|...:...:.||..|  :...||
E. coli   277 FFCASDIGWVVGHSYIVYAPLLAGM---ATIVYEGLPTWPDCGVWWTIVEKYQVSRMFSAPT--- 335

  Fly   332 DLVNTQKKLQVPLGRIKK--------AVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTETTAVIF 388
             .:...||.  |...|:|        ....|..:.......|...|:|..:.: |..||:...|.
E. coli   336 -AIRVLKKF--PTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDN-YWQTESGWPIM 396

  Fly   389 QSLPG-DSSDVVLNSVG--------HLTDHI--EAKVVDAEGRCVPFG--QPGELCVRGYTTMLG 440
            ....| |.....|.|.|        .|.:.:  |...|:.:|..|..|  .||  |::   |:.|
E. coli   397 AIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPG--CIQ---TIWG 456

  Fly   441 YHDDEE--KTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQ 503
              ||..  ||..::.:.....|.|..:.:|:||..|:||..:::...|..:..:|||:.:::||.
E. coli   457 --DDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTREIEESISSHPG 519

  Fly   504 VIEAHVIGVPDERLGEEVCAYV------RLEEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPID 562
            |.|..|:||.|...|:...|:|      .||:. |.|....:.:.|....::.:|..|.:|..:.
E. coli   520 VAEVAVVGVKDALKGQVAVAFVIPKESDSLEDR-DVAHSQEKAIMALVDSQIGNFGRPAHVWFVS 583

  Fly   563 AFPKTTSGKI 572
            ..|||.|||:
E. coli   584 QLPKTRSGKM 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	139/592 (23%)
		FACL_like_2	229..577	CDD:213284	97/397 (24%)
prpE	NP_414869.1	prpE	1..628	CDD:182517	140/595 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	0.910