DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12512 and FAT1

DIOPT Version :9

Sequence 1:NP_608924.1 Gene:CG12512 / 33766 FlyBaseID:FBgn0031703 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_009597.2 Gene:FAT1 / 852329 SGDID:S000000245 Length:669 Species:Saccharomyces cerevisiae


Alignment Length:563 Identity:122/563 - (21%)
Similarity:207/563 - (36%) Gaps:156/563 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 LQPGDAVGLWAPNY-LHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQ 159
            :|.||.|.:...|. |..:|.:      .|.::|..||:        || .|.|......:.|..
Yeast   134 VQAGDYVAIDCTNKPLFVFLWL------SLWNIGAIPAF--------LN-YNTKGTPLVHSLKIS 183

  Fly   160 NYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDSNDSLKGA--------LRFDDFLDLASKSE 216
            |..::..|                  |...:.|.:|.:.:|.|        |...|.:.....|:
Yeast   184 NITQVFID------------------PDASNPIRESEEEIKNALPDVKLNYLEEQDLMHELLNSQ 230

  Fly   217 REEVAKMQKSILPESACNIQ-----FTSGTTGNPKAACLTHH------NFVNNGIHVGNRNELEG 270
            ..|..:......|....:.:     :||||||.||:|.::..      ....:.:|:.|.:    
Yeast   231 SPEFLQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLHMTNES---- 291

  Fly   271 ERICVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAI----------VNEKCSVIHG 325
             .:...:|:||:...::...|.|:.|..:.| :..||.....:.:          |.|.|..:..
Yeast   292 -TVFTAMPLFHSTAALLGACAILSHGGCLAL-SHKFSASTFWKQVYLTGATHIQYVGEVCRYLLH 354

  Fly   326 TPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTE----TTA- 385
            ||      ::..:|:.    ::|.|...|  :.|.:.:|.|:..|:|.:...|..||    ||. 
Yeast   355 TP------ISKYEKMH----KVKVAYGNG--LRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTF 407

  Fly   386 --------------------VIFQSL-----PGDSSDVVLNSVGHLTDHIEAKVVDAEGRC--VP 423
                                :.||..     |.|.|.:..||               :|.|  .|
Yeast   408 QKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNS---------------KGFCEVAP 457

  Fly   424 FGQPGELCVRGY------TTMLGYHDDEEKTKETI------GNDRWLRTGDQFVLEANGYG--RI 474
            .|:|||:.:|.:      |:..||..:.::||..:      ..|.|.|.||  :|:|:.||  ..
Yeast   458 VGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGD--LLKADEYGLWYF 520

  Fly   475 VGRLKEMLIRGGENIFPKEIEDFLNA--HPQVIEAHVIGVPDERL-GEEVCAYVRLEEGVDPASF 536
            :.|:.:......||:...|:||.|.|  ..|..:..|:|:...:. |....|.::|.:  :....
Yeast   521 LDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYEGRAGFAVIKLTD--NSLDI 583

  Fly   537 TAETLKAYAKGKLAHFKVPRYVIP-----IDAFPKTTSGKIQK 574
            ||:|  ......|:...:|.|.:|     :|....|.:.||.|
Yeast   584 TAKT--KLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILK 624

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12512NP_608924.1 PRK08315 43..592 CDD:236236 122/563 (22%)
FACL_like_2 229..577 CDD:213284 95/421 (23%)
FAT1NP_009597.2 FATP_chFAT1_like 107..634 CDD:341260 122/563 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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