Protein Alignment CG12512 and ACS2

DIOPT Version :9

• Sequence 1: NP_608924.1
• Gene: CG12512 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_013254.1
• Gene: ACS2 / 850846
• SGDID: S000004143
• Length: 683
• Species: Saccharomyces cerevisiae
• Alignment Length: 606
• Identity: 130/606 - (21%)
• Similarity: 223/606 - (36%)
• Gaps: 161/606 - (26%)

  Fly    71 EGKRYSFKSLLQEADALAAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQG 135
            :.|..:|..||::...:|...:..|::.||.|.::.|......:.|:..||.|.....:...:..
Yeast   119 DNKIITFGELLRKVSQIAGVLKSWGVKKGDTVAIYLPMIPEAVIAMLAVARIGAIHSVVFAGFSA 183

  Fly   136 PEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDSNDSLK 200
            ..:...:...|.|.:|.                      .|.|| |..|..:.:.::   ::.|.
Yeast   184 GSLKDRVVDANSKVVIT----------------------CDEGK-RGGKTINTKKIV---DEGLN 222

  Fly   201 GALRFDDFLDLAS---------------KSER-----EEVAKMQKSILPESACNIQ------FTS 239
            |       :||.|               |:.|     ||.|| |::.||..:|:.:      :||
Yeast   223 G-------VDLVSRILVFQRTGTEGIPMKAGRDYWWHEEAAK-QRTYLPPVSCDAEDPLFLLYTS 279

  Fly   240 GTTGNPK------------AACLTHHNFVNNGIH-------VGNRNELEGERICVQVPMFHAFGV 285
            |:||:||            ||..|.:.|   .||       .|:...:.|....:..|:  ..|.
Yeast   280 GSTGSPKGVVHTTGGYLLGAALTTRYVF---DIHPEDVLFTAGDVGWITGHTYALYGPL--TLGT 339

  Fly   286 IISIMAALTKGATMVLPAAGFSPKDSLQAIVNEKCSVIHGTPT--MYVDLVNTQKKLQVPLGRIK 348
                 |::...:|...|..|    ...:.|...|.:..:..||  ..:..|...:..:.....::
Yeast   340 -----ASIIFESTPAYPDYG----RYWRIIQRHKATHFYVAPTALRLIKRVGEAEIAKYDTSSLR 395

  Fly   349 KAVTGGAIVSPQLIKDVRQVLNVEAVHSVYG-----------LTETTAVIFQSL-------PGDS 395
            ...:.|..:||.|         .|..|...|           .||:.:.:...|       ||.:
Yeast   396 VLGSVGEPISPDL---------WEWYHEKVGNKNCVICDTMWQTESGSHLIAPLAGAVPTKPGSA 451

  Fly   396 SDVVLNSVGHLTDHIEAKVVDAEGRCVPFGQPGELCVRG-----YTTMLGYHDDEEKTKETIGND 455
            :.........:.|.:..  |:.||..|    .|.|.|:.     ..::..:||..        .|
Yeast   452 TVPFFGINACIIDPVTG--VELEGNDV----EGVLAVKSPWPSMARSVWNHHDRY--------MD 502

  Fly   456 RWLR-------TGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVP 513
            .:|:       |||....:.:||..|.||:.:::...|..:...|||..::.|..|.||.|:|:|
Yeast   503 TYLKPYPGHYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTSEIEASISNHENVSEAAVVGIP 567

  Fly   514 DERLGEEVCAYVRLEEGV--------DPASFTAETLK----AYAKGKLAHFKVPRYVIPIDAFPK 566
            ||..|:.|.|||.|::|.        |....|.:.|:    ...:|::..|..|:.:|.:...|:
Yeast   568 DELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIGPFASPKTIILVRDLPR 632

  Fly   567 TTSGKIQKFKLVEAFKAKETE 587
            |.||||.: :::....:.|.|
Yeast   633 TRSGKIMR-RVLRKVASNEAE 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	130/606 (21%)
		FACL_like_2	229..577	CDD:213284	93/416 (22%)
ACS2	NP_013254.1	ACS	38..662	CDD:341270	130/606 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910