DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AAE2

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_177848.1	Gene:	AAE2 / 844060	AraportID:	AT1G77240	Length:	545	Species:	Arabidopsis thaliana

Alignment Length:	568	Identity:	157/568 - (27%)
Similarity:	236/568 - (41%)	Gaps:	81/568 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LELSASNFGDVEAIVSCHEGKRYS--FKSLLQEADALAAGFRKLGLQPGDAVGLWAPNYLHWYLG 115
            ||.:||.|||..:::.......:|  ....|:.|..|::.  .||:..|..|.:..||....|..
plant    20 LERAASVFGDSPSLLHTTTVHTWSETHSRCLRIASTLSSA--SLGINRGQVVSVIGPNVPSVYEL 82

  Fly   116 MMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKI 180
            ......:|.....:||......::..|.....|.:..                     |..:..:
plant    83 QFAVPMSGAVLNNINPRLDAHALSVLLRHSESKLVFV---------------------DHHSSSL 126

  Fly   181 RSEKFPHL------RSVII-DSNDSLKGALRFDDFLD-LASKSEREEVAKMQKSILPESACN--- 234
            ..|....|      |.||: |.||....:....|||| .....||.::  ..|.:.|:|...
plant   127 VLEAVSFLPKDERPRLVILNDGNDMPSSSSADMDFLDTYEGFMERGDL--RFKWVRPKSEWTPMV 189

  Fly   235 IQFTSGTTGNPKAACLTHHNFVNNGIHVGNRNELEGERICV-QVPMFHAFGVIISIMAALTKGAT 298
            :.:|||||.:||....:|.:...:.|:......|....:.: .:|||||.|...: .|....||.
plant   190 LNYTSGTTSSPKGVVHSHRSVFMSTINSLLDWSLPNRPVYLWTLPMFHANGWSYT-WATAAVGAR 253

  Fly   299 MVLPAAGFSPKDSLQAIVN--EKCSVIH--GTPTMYVDLVN--TQKKLQVPLGRIKKAVTGGAIV 357
            .:...     :..:..|.|  :|..|.|  ..|.:...|.|  .||.||.|:    |.:|.|| .
plant   254 NICVT-----RVDVPTIFNLIDKYQVTHMCAAPMVLNMLTNHPAQKPLQSPV----KVMTAGA-P 308

  Fly   358 SPQLIKDVRQVLNVEAVHSVYGLTETTAVI--------FQSLPGDSSDVVLNSVGHLT------- 407
            .|..:....:.|..:..|. ||:|||..::        :..|..|......:..|..|
plant   309 PPATVISKAEALGFDVSHG-YGMTETGGLVVSCALKPEWDRLEPDERAKQKSRQGIRTAVFAEVD 372

  Fly   408 --DHIEAKVVDAEGRCVPFGQPGELCVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANG 470
              |.|..|.|..:|..|     ||:..||.:.||||:.|.|.|..::..|.|..|||..|:..:|
plant   373 VRDPISGKSVKHDGATV-----GEIVFRGGSVMLGYYKDPEGTAASMREDGWFYTGDIGVMHPDG 432

  Fly   471 YGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVRLEEGVDPAS 535
            |..:..|.|:::|.|||||...|:|..|..:|.:.||.|:..||:..||..||:|.|:  ....|
plant   433 YLEVKDRSKDVVICGGENISSTELEAVLYTNPAIKEAAVVAKPDKMWGETPCAFVSLK--YHDGS 495

  Fly   536 FTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVEAFKA 583
            .|...::.:.|.||..:.|||.|:.::..|||::||||||.|.:..|:
plant   496 VTEREIREFCKTKLPKYMVPRNVVFLEELPKTSTGKIQKFLLRQMAKS 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	157/568 (28%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	116/374 (31%)
AAE2	NP_177848.1	ttLC_FACS_AEE21_like	13..538	CDD:341283	155/561 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3650
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810