DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AAE12

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_176764.1	Gene:	AAE12 / 842901	AraportID:	AT1G65890	Length:	578	Species:	Arabidopsis thaliana

Alignment Length:	582	Identity:	151/582 - (25%)
Similarity:	242/582 - (41%)	Gaps:	125/582 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 GK-RYSFKSLLQEADALAAGFRKLGLQPGDAVGLWAPN-----YLHWYLGMMGAARAGLTSVGLN 130
            || |:::.........|||....|.:...|.|.:.|||     .:|:.:.|.||.        ||
plant    36 GKTRFTWPQTYDRCCRLAASLISLNIGKNDVVSVVAPNTPAMYEMHFAVPMAGAV--------LN 92

  Fly   131 PAYQGPEIAYCLNKVNVKAII---APE-TFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSV 191
            |      |...|:..::.||:   .|: .|..:::..:.|:|...:|..|:         :|...
plant    93 P------INTRLDATSIAAILRHAKPKILFIYRSFEPLAREILQLLSSEDS---------NLNLP 142

  Fly   192 IIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKS-----ILPESAC--------NIQFTSGTTG 243
            :|..::.        ||....|..|.:....:|:.     :|....|        ::.:|||||.
plant   143 VIFIHEI--------DFPKRVSSEESDYECLIQRGEPTPLLLARMFCIQDEHDPISLNYTSGTTA 199

  Fly   244 NPKAACLTHHNFVNNGIHVGNRNELEGERI--CV----QVPMFHAFGVIISIMAALTKGATMVLP 302
            :||...::|     .|.::...:.:.|..:  |.    .:||||..|...: .....:|.|.|..
plant   200 DPKGVVISH-----RGAYLSTLSAIIGWEMGTCPVYLWTLPMFHCNGWTFT-WGTAARGGTSVCM 258

  Fly   303 AAGFSP---KDSLQAIVNEKCSVIHGTPTMY--------VDLVNTQKKLQVPLGRIKKAVTGGAI 356
            ....:|   |:.....|...|.|    ||::        :||.:....:.|        :|||:.
plant   259 RHVTAPEIYKNIEMHNVTHMCCV----PTVFNILLKGNSLDLSHRSGPVHV--------LTGGSP 311

  Fly   357 VSPQLIKDVRQVLNVEAVHSVYGLTETTA-VIF-------QSLPGDSSDVVLN-----SVGHLTD 408
            ....|:|.| |.|..:.:|: |||||.|. |:|       ..|| ::..:.|.     |:..||:
plant   312 PPAALVKKV-QRLGFQVMHA-YGLTEATGPVLFCEWQDEWNRLP-ENQQMELKARQGLSILGLTE 373

  Fly   409 HIEAKVVDAEGRCVPFGQP------GELCVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLE 467
                  ||...:......|      ||:.::|.:.|.||..:.:.|.|...:. ||.:||..|:.
plant   374 ------VDVRNKETQESVPRDGKTMGEIVMKGSSIMKGYLKNPKATYEAFKHG-WLNSGDVGVIH 431

  Fly   468 ANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVRLEEG-- 530
            .:|:..|..|.|:::|.|||||...|:|:.:..:|:|:|..|:.:|....||..||:|.||:|
plant   432 PDGHVEIKDRSKDIIISGGENISSVEVENIIYKYPKVLETAVVAMPHPTWGETPCAFVVLEKGET 496

  Fly   531 -----VDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVEAFKAKETE 587
                 .|........|..|.:..|.||..||.|:.:|..||..:|||.|.||.:..|....|
plant   497 NNEDREDKLVTKERDLIEYCRENLPHFMCPRKVVFLDELPKNGNGKILKPKLRDIAKGLVAE 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	151/582 (26%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	110/398 (28%)
AAE12	NP_176764.1	PLN03102	1..578	CDD:215576	151/582 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3650
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810