DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and ACOS5

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_176482.1	Gene:	ACOS5 / 842596	AraportID:	AT1G62940	Length:	542	Species:	Arabidopsis thaliana

Alignment Length:	592	Identity:	165/592 - (27%)
Similarity:	260/592 - (43%)	Gaps:	81/592 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNSKLQTISRYMLRQKCAFNSMRSISTSMPSLISHKHHIGKDPLVYRTIGQQLELSASNFGDVEA 65
            |.|:.|..:.|:         .||:..|:|  |..|..:.:..|      |.:|....|...|||
plant     1 MESQKQEDNEYI---------FRSLYPSVP--IPDKLTLPEFVL------QGVEEYTENVAFVEA 48

  Fly    66 IVSCHEGKRYSFKSLLQEADALAAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLN 130
            :.    ||..::..::::...||.....|||:.|..:.:..||...:.:..:|...||....|.|
plant    49 VT----GKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGAN 109

  Fly   131 PAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDS 195
            |.....||...:.....:.||...|    ||                .|::|...|    ||:..
plant   110 PTALVSEIKKQVEASGARGIITDAT----NY----------------EKVKSLGLP----VIVLG 150

  Fly   196 NDSLKGALRFDDFLDLASK---SEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHNFVN 257
            .:.::||:.:.|.|:...|   ::.||       ||....|.:.|:|||||..|...|||.|.:.
plant   151 EEKIEGAVNWKDLLEAGDKCGDTDNEE-------ILQTDLCALPFSSGTTGLQKGVMLTHRNLIA 208

  Fly   258 N--GIHVGNRNELEGERICV-QVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNEK 319
            |  ....|.|:|:.|:.:.: .:|.||.:| |:.|..|..|....|:..:.:..:..|.|::..:
plant   209 NLCSTLFGVRSEMIGQIVTLGLIPFFHIYG-IVGICCATMKNKGKVVAMSRYDLRIFLNALIAHE 272

  Fly   320 CSVIHGTPTMYVDLVNTQKKLQVPLGRIK--KAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTE 382
            .|.....|.:.::||......:..|.::|  ..:|..|.::|:|:...........|...|||||
plant   273 VSFAPIVPPIILNLVKNPIVDEFDLSKLKLQSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTE 337

  Fly   383 TTAVIFQSLPGDSSD----VVLNSVGHLTDHIEAKVVDAE-GRCVPFGQPGELCVRGYTTMLGYH 442
            .:.:....  ||...    ...||||.:..::|.|.:|.: ||.:|....||||||....|.||.
plant   338 HSCITLTH--GDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYF 400

  Fly   443 DDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEA 507
            .::|:|.:||....||.|||...::.:|...||.|:||::...|..:.|.|:|..|..||.|.:.
plant   401 MNKEETDKTIDEQGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDV 465

  Fly   508 HVIGVPDERLGEEVCAYVRL-----EEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKT 567
            .|:.:|||..||...|.|.:     |:..|..:|.|..:..|.|.:..||        :|:.||:
plant   466 AVVPLPDEEAGEIPAACVVINPKATEKEEDILNFVAANVAHYKKVRAVHF--------VDSIPKS 522

  Fly   568 TSGKIQK 574
            .||||.:
plant   523 LSGKIMR 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	155/550 (28%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	111/361 (31%)
ACOS5	NP_176482.1	PLN02330	1..542	CDD:215189	165/592 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710