DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and 4CL1

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_175579.1	Gene:	4CL1 / 841593	AraportID:	AT1G51680	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	593	Identity:	153/593 - (25%)
Similarity:	263/593 - (44%)	Gaps:	76/593 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QTISRYMLRQKCAFNSMRSISTSMPSLISHKHHIGKDPLVYRTIGQQLELSASNFGDVEAIVSCH 70
            |.:|:.|.:|....||.....:.:|. |...:|:.....:::.|        |.|.....:::..
plant     6 QAVSQVMEKQSNNNNSDVIFRSKLPD-IYIPNHLSLHDYIFQNI--------SEFATKPCLINGP 61

  Fly    71 EGKRYSFKSLLQEADALAAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQG 135
            .|..|::..:...:..:||.|.|||:...|.|.|..||...:.|..:.|:..|.|:...||.:..
plant    62 TGHVYTYSDVHVISRQIAANFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTP 126

  Fly   136 PEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDSNDSL- 199
            .|||......|.|.||.     ...|.:.::.:     ..|.|.:         .|.||.|:|:
plant   127 AEIAKQAKASNTKLIIT-----EARYVDKIKPL-----QNDDGVV---------IVCIDDNESVP 172

  Fly   200 --KGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHNFVNNGIHV 262
              :|.|||.:...  |.:|..||.. ...|.|:....:.::|||||.||...|||     .|:..
plant   173 IPEGCLRFTELTQ--STTEASEVID-SVEISPDDVVALPYSSGTTGLPKGVMLTH-----KGLVT 229

  Fly   263 GNRNELEGER-----------ICVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIV 316
            ....:::||.           :|| :||||.:.:...::..|..||.:::     .||..:..::
plant   230 SVAQQVDGENPNLYFHSDDVILCV-LPMFHIYALNSIMLCGLRVGAAILI-----MPKFEINLLL 288

  Fly   317 N--EKCSVIHG--TPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSV 377
            .  ::|.|...  .|.:.:.:..:.:..:..|..|:...:|.|    .|.|::...:|.:..::.
plant   289 ELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLSSIRVVKSGAA----PLGKELEDAVNAKFPNAK 349

  Fly   378 ----YGLTETTAVIFQSLPGDSSD---VVLNSVGHLTDHIEAKVVDAE-GRCVPFGQPGELCVRG 434
                ||:||...|:..|| |.:.:   |...:.|.:..:.|.|:||.: |..:...||||:|:||
plant   350 LGQGYGMTEAGPVLAMSL-GFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRG 413

  Fly   435 YTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLN 499
            :..|.||.::...|.|||..|.||.|||..:::.:....||.||||::...|..:.|.|:|..|.
plant   414 HQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLI 478

  Fly   500 AHPQVIEAHVIGVPDERLGEEVCAYVRLEEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAF 564
            .||.:.:..|:.:.:|..||...|:|...:   .:..:.:.:|.:...::..:|....|...::.
plant   479 GHPDITDVAVVAMKEEAAGEVPVAFVVKSK---DSELSEDDVKQFVSKQVVFYKRINKVFFTESI 540

  Fly   565 PKTTSGKI 572
            ||..||||
plant   541 PKAPSGKI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	144/556 (26%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	98/367 (27%)
4CL1	NP_175579.1	PLN02246	16..560	CDD:215137	149/583 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710