DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12512 and AT1G21540

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_173573.1	Gene:	AT1G21540 / 838755	AraportID:	AT1G21540	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	605	Identity:	157/605 - (25%)
Similarity:	241/605 - (39%)	Gaps:	121/605 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 HHIGKDPLVYRTIGQQLELSASNFGDVEAIV----SCHEGKRYSFKSLLQEADALAAGFRKLGLQ 97
            |.....||   |:...|:.:||.:||..:|:    :.|.... :....|:.|.||.:.  .||:.
plant     7 HPSNSTPL---TVLGFLDRAASVYGDCPSILHTTNTVHTWSE-THNRCLRIASALTSS--SLGIN 65

  Fly    98 PGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYY 162
            .|..|.:..||....|........:|.....:||......::..|.....|.:     |...|..
plant    66 RGQVVSVVGPNVPSVYELQFAVPMSGAILNNINPRLDAHALSVLLRHSESKLV-----FVDPNSI 125

  Fly   163 EILRDICPEISDADTGKIRSEKFPHLRSVIIDSNDSLKGAL---RFDDFLDLASKSEREEVAKMQ 224
            .::.:.        ...:|..:.|||  |::| :|...|:|   ...|||| ..:...|......
plant   126 SVVLEA--------VSFMRQNEKPHL--VLLD-DDQEDGSLSPSAASDFLD-TYQGVMERGDSRF 178

  Fly   225 KSILPESACN---IQFTSGTTGNPKAACLTHH-------------NFVNNGIHVGNRNELEGERI 273
            |.|.|::...   :.:|||||.:||...|:|.             :|.|..:::..
plant   179 KWIRPQTEWQPMILNYTSGTTSSPKGVVLSHRAIFMLTVSSLLDWHFPNRPVYLWT--------- 234

  Fly   274 CVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNEKCSVIHGTPTMYVDLVN--- 335
               :|||||.|          .|.|....|.|          ....|:.....||:| ||::
plant   235 ---LPMFHANG----------WGYTWGTAAVG----------ATNVCTRRVDAPTIY-DLIDKHH 275

  Fly   336 --------------TQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTETTAV 386
                          |....:.||....:.:|.|| ..|..|....:.|.....|. ||||||...
plant   276 VTHMCAAPMVLNMLTNYPSRKPLKNPVQVMTAGA-PPPAAIISRAETLGFNVGHG-YGLTETGGP 338

  Fly   387 IFQ---SLPGDSSDVV----------LNSVG----HLTDHIEAKVVDAEGRCVPFGQPGELCVRG 434
            :..   ....|..|.:          :.::|    .:.|....|.|:.:|..|     ||:.::|
plant   339 VVSCAWKAEWDHLDPLERARLKSRQGVRTIGFAEVDVRDPRTGKSVEHDGVSV-----GEIVLKG 398

  Fly   435 YTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLN 499
            .:.||||:.|.|.|...:..|.|..:||..|:..:||..:..|.|:::|.|||||...|:|..|.
plant   399 GSVMLGYYKDPEGTAACMREDGWFYSGDVGVIHEDGYLEVKDRSKDVIICGGENISSAEVETVLY 463

  Fly   500 AHPQVIEAHVIGVPDERLGEEVCAYVRLE-EGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDA 563
            .:|.|.||.|:..||:..||..||:|.|: :.......|...::.:.|.:|..:.|||.||..:.
plant   464 TNPVVKEAAVVAKPDKMWGETPCAFVSLKYDSNGNGLVTEREIREFCKTRLPKYMVPRKVIFQEE 528

  Fly   564 FPKTTSGKIQKFKLVEAFKA 583
            .|||::||||||.|.:..|:
plant   529 LPKTSTGKIQKFLLRQMAKS 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	156/599 (26%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	110/398 (28%)
AT1G21540	NP_173573.1	ttLC_FACS_AEE21_like	12..543	CDD:341283	154/593 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3650
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810