DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and OPCL1

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_564115.1	Gene:	OPCL1 / 838639	AraportID:	AT1G20510	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	147/567 - (25%)
Similarity:	260/567 - (45%)	Gaps:	72/567 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 STSMPSLISHKHHIGKDPLVYRTIGQQLELSASNFGDVEAIVSCHEGKRYSFKSLLQEADALAAG 90
            |..:.:.||.:.|.|:...:..:.||.|                      :|..|.:..:::|..
plant    31 SLDVTTFISSQAHRGRIAFIDASTGQNL----------------------TFTELWRAVESVADC 73

  Fly    91 FRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPET 155
            ..::|::.|..|.|.:||.:.:.:..:.....|......||.....|||..:...|  .::|
plant    74 LSEIGIRKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNTSNEIAKQIKDSN--PVLA--- 133

  Fly   156 FKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDSN--DSLKGALRFDDFLDLASKSERE 218
            |.|.       .:.|:||.|      ::|.|   .|::|..  ||:....|..:.:.......|
plant   134 FTTS-------QLLPKISAA------AKKLP---IVLMDEERVDSVGDVRRLVEMMKKEPSGNR- 181

  Fly   219 EVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHNFVNNGIHVGNR-NELEGER--ICVQVPMF 280
                :::.:..:....:.::|||||..|....:|.|.:.....:.|| ...:||:  ||. ||||
plant   182 ----VKERVDQDDTATLLYSSGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFICT-VPMF 241

  Fly   281 HAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNEKCSVIHGTPTMYVDLVN--TQKKLQVP 343
            |.:|:.......|..|:|::: .:.|...:.:.||...:.:.:...|.:.|.:||  .|.|.:..
plant   242 HIYGLAAFATGLLAYGSTIIV-LSKFEMHEMMSAIGKYQATSLPLVPPILVAMVNGADQIKAKYD 305

  Fly   344 LGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNS-----V 403
            |..:...:.|||.:|.::.:...:......:...|||||:|.:      |.|:|.|..|     .
plant   306 LSSMHTVLCGGAPLSKEVTEGFAEKYPTVKILQGYGLTESTGI------GASTDTVEESRRYGTA 364

  Fly   404 GHLTDHIEAKVVD-AEGRCVPFGQPGELCVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLE 467
            |.|:..:|.::|| ..|:.:...|.|||.::|.:.|.||..:||.|..|:.::.||||||...::
plant   365 GKLSASMEGRIVDPVTGQILGPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYID 429

  Fly   468 ANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVRLEEGVD 532
            .:|:..:|.||||::...|..:.|.|:|..|..||::.:|.||..||:.:|:...|||..:.|
plant   430 EDGFIFVVDRLKELIKYKGYQVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTG-- 492

  Fly   533 PASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVE 579
             :|.:.:|:..:...::|.:|..|.|..:.:.||..||||.:..|::
plant   493 -SSLSEKTIMEFVAKQVAPYKRIRKVAFVSSIPKNPSGKILRKDLIK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	142/550 (26%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	107/358 (30%)
OPCL1	NP_564115.1	4CL	26..536	CDD:341230	146/563 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710