DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AT1G20500

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_173474.5	Gene:	AT1G20500 / 838638	AraportID:	AT1G20500	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	596	Identity:	149/596 - (25%)
Similarity:	272/596 - (45%)	Gaps:	92/596 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YMLRQKCAF--NSMRSISTSMPSLISHKHHIGKDPLVYRTIGQQLELSASNFGDVEAIVSCHEGK 73
            |..||..:.  |..|.::|    .||.:.|.||...:....||.|     .|.|:
plant    24 YSKRQPLSLPPNLSRDVTT----FISSQPHRGKTAFIDAATGQCL-----TFSDL---------- 69

  Fly    74 RYSFKSLLQEADALAAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEI 138
               ::::.:.||.|   :.::|::.||.|.:.:||.:  ::.::
plant    70 ---WRAVDRVADCL---YHEVGIRRGDVVLILSPNSI--FIPVV--------------------- 105

  Fly   139 AYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDAD-----TGKIRSEKFPHLRSVIIDSND- 197
              ||:.:::.|:     |.|.|......:|..:|:|::     |.:..:.|.|...||::..::
plant   106 --CLSVMSLGAV-----FTTANTLNTSGEISKQIADSNPTLVFTTRQLAPKLPVAISVVLTDDEV 163

  Fly   198 --SLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHN------ 254
              .|..|:|....|....|.| ....:::..:..:....:.::|||||..|....:|.|
plant   164 YQELTSAIRVVGILSEMVKKE-PSGQRVRDRVNQDDTAMMLYSSGTTGPSKGVISSHRNLTAHVA 227

  Fly   255 -FVNNGIHVGNRNELEGERICVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNE 318
             |:::.:   .|:::   .||. |||||.:|::...|..:..|:|:|: ...|...|.:.|:...
plant   228 RFISDNL---KRDDI---FICT-VPMFHTYGLLTFAMGTVALGSTVVI-LRRFQLHDMMDAVEKH 284

  Fly   319 KCSVIHGTPTMYVDLVNTQK--KLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLT 381
            :.:.:...|.:.|.::|...  |.:..|..:|....|||.:|.::.:...:......:...|.||
plant   285 RATALALAPPVLVAMINDADLIKAKYDLSSLKTVRCGGAPLSKEVTEGFLEKYPTVDILQGYALT 349

  Fly   382 ETT-AVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVDAE-GRCVPFGQPGELCVRGYTTMLGYHDD 444
            |:. ...|.:...:|..  ..:.|.||..:||::||.. ||.:...|.|||.::|.:...||..:
plant   350 ESNGGGAFTNSAEESRR--YGTAGTLTSDVEARIVDPNTGRFMGINQTGELWLKGPSISKGYFKN 412

  Fly   445 EEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHV 509
            :|.|.|||..:.||:|||...::.:|:..:|.||||::...|..:.|.|:|..|..||.:::|.|
plant   413 QEATNETINLEGWLKTGDLCYIDEDGFLFVVDRLKELIKYKGYQVPPAELEALLITHPDILDAAV 477

  Fly   510 IGVPDERLGEEVCAY-VRLEEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQ 573
            |..||:..|:...|| ||..|    ::.:.:.:..:...::|.:|..|.|..|::.|||.|||..
plant   478 IPFPDKEAGQYPMAYVVRKHE----SNLSEKQVIDFISKQVAPYKKIRKVSFINSIPKTASGKTL 538

  Fly   574 KFKLVEAFKAK 584
            :..|::...:|
plant   539 RKDLIKLATSK 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	138/562 (25%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	102/359 (28%)
AT1G20500	NP_173474.5	PLN02574	16..542	CDD:215312	147/587 (25%)
AT1G20500	NP_173474.5	4CL	32..542	CDD:213272	144/579 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710