DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12512 and AT5G63380

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_201143.1	Gene:	AT5G63380 / 836457	AraportID:	AT5G63380	Length:	562	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	157/594 - (26%)
Similarity:	271/594 - (45%)	Gaps:	98/594 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FNSMRSISTSMPSLISHKHHIGKDPLVYRTIGQQLELSAS-------NFGDVEAIVSCHEGKRYS 76
            ::|:|. |.|:|.:        ..||........|.|.:|       |...:..:|:...|...:
plant    24 YHSLRP-SLSLPPI--------DQPLSAAEFALSLLLKSSPPATAGKNIEALTYLVNSSSGDNLT 79

  Fly    77 FKSLLQEADALAAGFRKL--GLQPGDAVGLWAPNYLH---WYLGMMGAARAGLTSVGL-----NP 131
            :..||:...:||...|:.  .|...:...:.:|:.|.   .||.:|        |:|:     ||
plant    80 YGELLRRVRSLAVSLRERFPSLASRNVAFILSPSSLDIPVLYLALM--------SIGVVVSPANP 136

  Fly   132 AYQGPEIAYCLNKVNV-KAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDS 195
            .....|:::   :|.| :.:||..|.:|                  ..|::|...| |.:|::||
plant   137 IGSESEVSH---QVEVSEPVIAFATSQT------------------VKKLQSSSLP-LGTVLMDS 179

  Fly   196 NDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHNFVNNGI 260
            .          :||...::|:...|...|..:.......|.|:|||||..|...|||.|.:.: .
plant   180 T----------EFLSWLNRSDSSSVNPFQVQVNQSDPAAILFSSGTTGRVKGVLLTHRNLIAS-T 233

  Fly   261 HVGNRNELEG----ERI-CVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNEKC 320
            .|.::..|:.    :|: ...:|:||.||.::.| .|::.|.|:|| ...|..:...:|:...|.
plant   234 AVSHQRTLQDPVNYDRVGLFSLPLFHVFGFMMMI-RAISLGETLVL-LGRFELEAMFKAVEKYKV 296

  Fly   321 SVIHGTPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVL-NVEAVHSVYGLTETT 384
            :.:..:|.:.|.||.::...:..|..::....|||.:...:.:..:|.. :|:.|.. |||||::
plant   297 TGMPVSPPLIVALVKSELTKKYDLRSLRSLGCGGAPLGKDIAERFKQKFPDVDIVQG-YGLTESS 360

  Fly   385 AVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVD-AEGRCVPFGQPGELCVRGYTTMLGYHDDEEKT 448
            .....:. |....|...|||.:::::|||:|| :.|..:|.|:.|||.:||...|.||..:|:.:
plant   361 GPAASTF-GPEEMVKYGSVGRISENMEAKIVDPSTGESLPPGKTGELWLRGPVIMKGYVGNEKAS 424

  Fly   449 KETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVP 513
            .||:..:.||:|||....::..:..||.||||::......:.|.|:|..|:::|.||:|.|:..|
plant   425 AETVDKEGWLKTGDLCYFDSEDFLYIVDRLKELIKYKAYQVPPVELEQILHSNPDVIDAAVVPFP 489

  Fly   514 DERLGEEVCAYVRLEEG--------VDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSG 570
            ||..||...|::..:.|        :|   |.|:.:..|.|.:...|        |:|.||..:|
plant   490 DEDAGEIPMAFIVRKPGSNLNEAQIID---FVAKQVTPYKKVRRVAF--------INAIPKNPAG 543

  Fly   571 KIQKFKLVE 579
            ||.:.:|.:
plant   544 KILRRELTK 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	152/570 (27%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	109/362 (30%)
AT5G63380	NP_201143.1	PLN02574	17..562	CDD:215312	157/594 (26%)
AT5G63380	NP_201143.1	4CL	48..550	CDD:213272	149/557 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810