DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and 4CL8

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_198628.2	Gene:	4CL8 / 833792	AraportID:	AT5G38120	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	150/591 - (25%)
Similarity:	254/591 - (42%)	Gaps:	80/591 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NSMRSIS---------TSMPSLISHKHHI---GKDPLVYRTIGQQLELSASNFGDVEAIVSCHEG 72
            ||.||.|         ||..:..|.:..:   .|:.|...|.     :|:..:....|.:.....
plant     3 NSQRSSSLIDPRNGFCTSNSTFYSKRKPLALPSKESLDITTF-----ISSQTYRGKTAFIDAATD 62

  Fly    73 KRYSFKSLLQEADALA-AGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGP 136
            .|.||..|....|.:| .....:|::.||.|.:.:||.:...:..:.....|......||.....
plant    63 HRISFSDLWMAVDRVADCLLHDVGIRRGDVVLVLSPNTISIPIVCLSVMSLGAVLTTANPLNTAS 127

  Fly   137 EIAYCLNKVNVK-AIIAPETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDS-NDSL 199
            ||...:...|.| |...||             :.|:|:.:..            |::::. .|:|
plant   128 EILRQIADSNPKLAFTTPE-------------LAPKIASSGI------------SIVLERVEDTL 167

  Fly   200 ---KGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHNFVNN-GI 260
               :|.....:..::..|....:..:.|  :..:....:.::|||||..|....:|.|.:.: ..
plant   168 RVPRGLKVVGNLTEMMKKEPSGQAVRNQ--VHKDDTAMLLYSSGTTGRSKGVNSSHGNLIAHVAR 230

  Fly   261 HVGNRNELEGERICVQVPMFHAFGVIISIMAALTKGATMV-LPAAGFSPKDSLQAIVNEKCSVIH 324
            ::....|...:.....||:||.||::..::|.|..|.|:| ||.  |...:.:.|:...:.:.:.
plant   231 YIAEPFEQPQQTFICTVPLFHTFGLLNFVLATLALGTTVVILPR--FDLGEMMAAVEKYRATTLI 293

  Fly   325 GTPTMYVDLVN----TQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTETTA 385
            ..|.:.|.::|    ..||..|...|..:.  |||.:|.::.:...:......|:..|.|||:..
plant   294 LVPPVLVTMINKADQIMKKYDVSFLRTVRC--GGAPLSKEVTQGFMKKYPTVDVYQGYALTESNG 356

  Fly   386 VIFQSLPGDSSDVVLNS-----VGHLTDHIEAKVVDAE-GRCVPFGQPGELCVRGYTTMLGYHDD 444
            .      |.|.:.|..|     ||.|:..:||::||.. |:.:...|.|||.::|.:...||..:
plant   357 A------GASIESVEESRRYGAVGLLSCGVEARIVDPNTGQVMGLNQTGELWLKGPSIAKGYFRN 415

  Fly   445 EEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHV 509
            ||   |.|.::.||:|||...::.:|:..||.||||::...|..:.|.|:|..|..||.:::|.|
plant   416 EE---EIITSEGWLKTGDLCYIDNDGFLFIVDRLKELIKYKGYQVPPAELEALLLNHPDILDAAV 477

  Fly   510 IGVPDERLGEEVCAYVRLEEGVDPASFTAE-TLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQ 573
            |..||:..|:...|||..:    |.|...| .:..:...::|.:|..|.|..||:.|||.|||..
plant   478 IPFPDKEAGQFPMAYVARK----PESNLCEKKVIDFISKQVAPYKKIRKVAFIDSIPKTPSGKTL 538

  Fly   574 KFKLVE 579
            :..|::
plant   539 RKDLIK 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	141/556 (25%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	106/360 (29%)
4CL8	NP_198628.2	PLN02574	17..542	CDD:215312	144/573 (25%)
4CL8	NP_198628.2	4CL	33..542	CDD:213272	141/557 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710