DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AT4G19010

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_193636.1	Gene:	AT4G19010 / 827639	AraportID:	AT4G19010	Length:	566	Species:	Arabidopsis thaliana

Alignment Length:	609	Identity:	163/609 - (26%)
Similarity:	268/609 - (44%)	Gaps:	129/609 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FNSMRSISTS-MPS--------------LISHKHHIGKDPLVYRTIGQQLELSASNFGDVEAIVS 68
            |:|...|.|| .||              |.|||||                      ||. |::.
plant    25 FSSKTGIYTSKFPSLHLPVDPNLDAVSALFSHKHH----------------------GDT-ALID 66

  Fly    69 CHEGKRYSFKSLLQEADALAAG-FRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNP- 131
            ...|...|...|.....::||| :..||::.||.|.|..||.:::.:..:.....|.....:||
plant    67 SLTGFSISHTELQIMVQSMAAGIYHVLGVRQGDVVSLVLPNSVYFPMIFLSLISLGAIVTTMNPS 131

  Fly   132 -----------------AYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGK 179
                             |:...|....|:.:.|..|...|::                 |.|:.:
plant   132 SSLGEIKKQVSECSVGLAFTSTENVEKLSSLGVSVISVSESY-----------------DFDSIR 179

  Fly   180 IRSEKFPHLRSVIIDSNDSL-KGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTG 243
            |.:.||   .|::.:|...: |..::.||                        ...|.::|||||
plant   180 IENPKF---YSIMKESFGFVPKPLIKQDD------------------------VAAIMYSSGTTG 217

  Fly   244 NPKAACLTHHNFV-NNGIHV---GNRNELEGER--ICVQVPMFHAFGVIISIMAALTKGATMVLP 302
            ..|...|||.|.: :..:.|   .::.|..|..  ....:|:.|.:|:.:.:|..|:.|:|:|:
plant   218 ASKGVLLTHRNLIASMELFVRFEASQYEYPGSSNVYLAALPLCHIYGLSLFVMGLLSLGSTIVV- 281

  Fly   303 AAGFSPKDSLQAIVNEKCSVIHGTPTMYVDLVNTQKKLQVPLGRI----KKAVTGGAIVSPQLIK 363
            ...|...|.:..|...|.:.....|.|.:.|.   ||.:...|.:    |:..:|.|.:|.:.|:
plant   282 MKRFDASDVVNVIERFKITHFPVVPPMLMALT---KKAKGVCGEVFKSLKQVSSGAAPLSRKFIE 343

  Fly   364 DVRQVL-NVEAVHSVYGLTETTAVIFQSLPGDSSDVV--LNSVGHLTDHIEAKVVD-AEGRCVPF 424
            |..|.| :|:.:.. ||:||:|||   ...|.:|:.:  .:|||.|..:::||||| :.|..:|.
plant   344 DFLQTLPHVDLIQG-YGMTESTAV---GTRGFNSEKLSRYSSVGLLAPNMQAKVVDWSSGSFLPP 404

  Fly   425 GQPGELCVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENI 489
            |..|||.::|...|.||.::.:.|:.:|..|.||||||....:.:||..||.|:||::...|..|
plant   405 GNRGELWIQGPGVMKGYLNNPKATQMSIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQI 469

  Fly   490 FPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAY-VRLEEGVDPASFTAETLKAYAKGKLAHFK 553
            .|.::|..|.:||.:|:|.|...|:|..||...|: ||.:|    .:.:.|.:.:|...::|.::
plant   470 APADLEAVLVSHPLIIDAAVTAAPNEECGEIPVAFVVRRQE----TTLSEEDVISYVASQVAPYR 530

  Fly   554 VPRYVIPIDAFPKTTSGKIQKFKL 577
            ..|.|:.:::.||:.:|||.:.:|
plant   531 KVRKVVMVNSIPKSPTGKILRKEL 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	150/570 (26%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	113/362 (31%)
AT4G19010	NP_193636.1	PLN02574	9..566	CDD:215312	163/609 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810