DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AT4G05160

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_192425.1	Gene:	AT4G05160 / 825864	AraportID:	AT4G05160	Length:	544	Species:	Arabidopsis thaliana

Alignment Length:	582	Identity:	159/582 - (27%)
Similarity:	265/582 - (45%)	Gaps:	74/582 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KHHIGKDPLVYRTIGQQLEL--------------SASNFGDVEAIVSCHEGKRYSFKSLLQEADA 86
            |...|:|. :||::...|.|              ::|::....||.....|...:|..|......
plant     3 KSGYGRDG-IYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKLAIADSDTGDSLTFSQLKSAVAR 66

  Fly    87 LAAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAII 151
            ||.||.:||::..|.|.::|||...:.|..:.....|......||.|...|::..:...|.|.||
plant    67 LAHGFHRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIII 131

  Fly   152 APETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVIIDSNDSLK---GA----LRFDDFL 209
            :..                ::.|    ||:....|   .|::.|.|:::   |:    |.||:.:
plant   132 SVN----------------QLFD----KIKGFDLP---VVLLGSKDTVEIPPGSNSKILSFDNVM 173

  Fly   210 DLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTHHNFVNNGIHVGNRNELEGER-- 272
            :|:.........::::|    ....:.::|||||..|...|||.||:...:.|....:|.||.
plant   174 ELSEPVSEYPFVEIKQS----DTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHG 234

  Fly   273 --ICVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVN--EKCSVIH--GTPTMYV 331
              :|. :||||.||:.:...:.|.:|..:|..|     :..|:.::.  ||..|.|  ..|.:::
plant   235 VFLCF-LPMFHVFGLAVITYSQLQRGNALVSMA-----RFELELVLKNIEKFRVTHLWVVPPVFL 293

  Fly   332 DLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDV-RQVLNVEAVHSVYGLTETTAVIFQSLP--G 393
            .|.......:..|..:|...:|.|.:...|:::. |.:.||..:.. ||:|||..::....|  |
plant   294 ALSKQSIVKKFDLSSLKYIGSGAAPLGKDLMEECGRNIPNVLLMQG-YGMTETCGIVSVEDPRLG 357

  Fly   394 DSSDVVLNSVGHLTDHIEAKVVDAE-GRCVPFGQPGELCVRGYTTMLGYHDDEEKTKETIGNDRW 457
            ..:.   .|.|.|...:||::|..| |:..|..|.||:.|||...|.||.::.:.|||||....|
plant   358 KRNS---GSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGPNMMKGYLNNPQATKETIDKKSW 419

  Fly   458 LRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVC 522
            :.|||......:|...:|.|:||::...|..:.|.|:|..|.:||.:::|.||..|||..||...
plant   420 VHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVSHPDILDAVVIPFPDEEAGEVPI 484

  Fly   523 AYVRLEEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVEAFKAK 584
            |:|.....   :|.|.:.::.:...::|.:|..|.|..|...||:.:|||.:.:||:..::|
plant   485 AFVVRSPN---SSITEQDIQKFIAKQVAPYKRLRRVSFISLVPKSAAGKILRRELVQQVRSK 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	156/575 (27%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	109/359 (30%)
AT4G05160	NP_192425.1	4CL	21..536	CDD:341230	150/554 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.710