DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AAE3

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_190468.1	Gene:	AAE3 / 824060	AraportID:	AT3G48990	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	152/550 - (27%)
Similarity:	248/550 - (45%)	Gaps:	54/550 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TIGQQLELSASNFGDVEAI-VSCHEGKRYSFKSLLQEADALAAG--FRKLGLQPGDAVGLWAPNY 109
            |:...||..|..|.|..|: ||   ||.....:.|.:....||.  ....|::|||.|.|..||.
plant     5 TLSGLLENVAKKFPDRRALSVS---GKFNLTHARLHDLIERAASRLVSDAGIKPGDVVALTFPNT 66

  Fly   110 LHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISD 174
            :.:.:..:...||..|:..||.||...|..:.|:..:.|.::   |.|..|
plant    67 VEFVIMFLAVIRARATAAPLNAAYTAEEFEFYLSDSDSKLLL---TSKEGN-------------- 114

  Fly   175 ADTGKIRSE-KFPHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSIL--PESACNIQ 236
            |...:..|: |..|:.:.::|:...|           :.|.::.:.|......::  |:......
plant   115 APAQEAASKLKISHVTATLLDAGSDL-----------VLSVADSDSVVDSATELVNHPDDGALFL 168

  Fly   237 FTSGTTGNPKAACLTHHNFVNNGIHVGNRNEL-EGERICVQVPMFHAFGVIISIMAALTKGATMV 300
            .|||||..||...||..|..::..::....:| |.:...:.:|:||..|::..::::|..||.:.
plant   169 HTSGTTSRPKGVPLTQLNLASSVKNIKAVYKLTESDSTVIVLPLFHVHGLLAGLLSSLGAGAAVT 233

  Fly   301 LPAAG-FSPKDSLQAIVNEKCSVIHGTPTMY---VDLVNTQKKLQVPLGRIKKAVTGGAIVSPQL 361
            ||||| ||.......:.....:.....||::   :|...:..:.:.|..|..::.:  |.::|.:
plant   234 LPAAGRFSATTFWPDMKKYNATWYTAVPTIHQIILDRHASHPETEYPKLRFIRSCS--ASLAPVI 296

  Fly   362 IKDVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVDAEGRCVPFGQ 426
            :..:.:......:.: |.:||.|.::..:...:.......|||..... |..:::.:|.......
plant   297 LSRLEEAFGAPVLEA-YAMTEATHLMSSNPLPEEGPHKPGSVGKPVGQ-EMAILNEKGEIQEPNN 359

  Fly   427 PGELCVRGYTTMLGYHDDEEKTKE--TIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENI 489
            .||:|:||.....||.::.|..|.  ..|   |..|||....:.:||..:|||:||::.||||.|
plant   360 KGEVCIRGPNVTKGYKNNPEANKAGFEFG---WFHTGDIGYFDTDGYLHLVGRIKELINRGGEKI 421

  Fly   490 FPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVRLEEGVDPASFTAETLKAYAKGKLAHFKV 554
            .|.|::..|..||.|.:....|||||:.|||:...|...||   .:.|.|.:||:.|..||.|||
plant   422 SPIEVDAVLLTHPDVSQGVAFGVPDEKYGEEINCAVIPREG---TTVTEEDIKAFCKKNLAAFKV 483

  Fly   555 PRYVIPIDAFPKTTSGKIQKFKLVEAFKAK 584
            |:.|...|..|||.|||||:..:.:.|..|
plant   484 PKRVFITDNLPKTASGKIQRRIVAQHFLEK 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	151/549 (28%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	107/354 (30%)
AAE3	NP_190468.1	FACL_fum10p_like	18..508	CDD:341249	145/530 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.710