DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and AAE13

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001319565.1	Gene:	AAE13 / 820862	AraportID:	AT3G16170	Length:	608	Species:	Arabidopsis thaliana

Alignment Length:	640	Identity:	153/640 - (23%)
Similarity:	259/640 - (40%)	Gaps:	130/640 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SLISHK-----HHIGKDPLVYRTIGQQLELSASNF-------------GDV---------EAIVS 68
            |||:|:     :.|...||:.|:.......|.|.|             |.:         ||..|
plant    14 SLINHRLNHNSYAILSSPLLPRSHPASTSFSNSGFRFFQSNHLFSSQSGSLMEVFKAAFSEASNS 78

  Fly    69 CH------EGKRYSFKSLLQEADALAAGFRK---------------LGLQPGDAVGLWAPNYLHW 112
            |.      :||.||:..|...|..::..|.|               .|...|..:|:.|.....:
plant    79 CDRIAIKADGKSYSYGQLTSSALRISKLFLKDDTTNGGQETKKYEGFGSLKGARIGIVAKPSAEF 143

  Fly   113 YLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADT 177
            ..|::|...:|..:|.|..:|...|:.:.:|..::..:::     |:::.|.::.|.     |.:
plant   144 VAGVLGTWFSGGVAVPLALSYPEAELLHVMNDSDISLLLS-----TEDHSETMKTIA-----AKS 198

  Fly   178 GKIRSEKFPHLRSVIIDSNDSLKGALRF-DDFLDLASKSEREEVAKMQKSILPESACNIQFTSGT 241
            |    .:| ||...:::|........:| ||..:...|            .|.:.|. |.:||||
plant   199 G----ARF-HLIPPVVNSTSETVACNQFQDDSFEAEGK------------FLDDPAL-IVYTSGT 245

  Fly   242 TGNPKAACLTHHNFVNNGIHVGNR--NELEGERICVQVPMFHAFGVIISIMAALTKGATMVLPAA 304
            ||.||....| ||.:|:.:.:...  .....:.....:|:.|..|:..::.|.|...:.:
plant   246 TGKPKGVVHT-HNSINSQVRMLTEAWEYTSADHFLHCLPLHHVHGLFNALFAPLYARSLV----- 304

  Fly   305 GFSPKDSLQAI--------------VNEKCSVIHGTPTMYVDLVNTQKKLQVPL-------GRIK 348
            .|.||.|:..|              .|:..:|..|.||||..|:...:.:...:       .|..
plant   305 EFLPKFSVSGIWRRWRESYPVNDEKTNDSITVFTGVPTMYTRLIQGYEAMDKEMQDSSAFAARKL 369

  Fly   349 KAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSVGHLTDHIEAK 413
            :.:..|:...|:.:....:.:....:...||:||....:...|.|..:   ..:||.....:|||
plant   370 RLMMSGSSALPRPVMHQWESITGHRLLERYGMTEFVMAMSNPLRGARN---AGTVGKPLPGVEAK 431

  Fly   414 VV----DAEGRCVPFGQPGELCVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRI 474
            :.    ||.|       .||:||:..:....|.:..|.|||:...|.:.:|||...::.:||..|
plant   432 IKEDENDANG-------VGEICVKSPSLFKEYWNLPEVTKESFTEDGYFKTGDAGRVDEDGYYVI 489

  Fly   475 VGRLKEMLIR-GGENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYV--------RLEEG 530
            :||....::: ||..:...|||..|..||.|.|..|:|:.|...||.|.|.:        |.|:.
plant   490 LGRNSADIMKVGGYKLSALEIESTLLEHPTVAECCVLGLTDNDYGEAVTAIIIAESAAKKRREDE 554

  Fly   531 VDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVEAFKAKE 585
            ..|. .|.|.|..:||.|||.:|:|..::..::.|:...||:.|.:|.::.:.:|
plant   555 SKPV-ITLEELCGWAKDKLAPYKLPTRLLIWESLPRNAMGKVNKKELKKSLENQE 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	148/623 (24%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	101/383 (26%)
AAE13	NP_001319565.1	MCS	80..597	CDD:213307	134/561 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810