Protein Alignment CG12512 and ACSBG2

DIOPT Version :9

• Sequence 1: NP_608924.1
• Gene: CG12512 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001276106.1
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 138/628 - (21%)
• Similarity: 247/628 - (39%)
• Gaps: 121/628 - (19%)

  Fly    36 KHHIGKD-PLVYRTIGQQLELSASNFGDVEAIVSCHEGKRY---SFKSLLQEADALAAGFRKLGL 96
            ||..|.: |:   ||.:....|.:.||...|:.| ..||::   :|....:.....|....||||
Human    42 KHGPGHETPM---TIPEFFRESVNRFGTYPALAS-KNGKKWEILNFNQYYEACRKAAKSLIKLGL 102

  Fly    97 QPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNY 161
            :....||:...|...|::..:||..||...||:..........|.:....|..::.....:.|..
Human   103 ERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKI 167

  Fly   162 YEILRDICPEISDADTGKIRSEKFPHLRSVIIDSNDSLKGALRFDDFLDLASK---SEREEVAKM 223
            ..|     |:.|......|...:.|      :..|::|   ..:|||::|...   ::.|:|.:.
Human   168 LSI-----PQSSLEPLKAIIQYRLP------MKKNNNL---YSWDDFMELGRSIPDTQLEQVIES 218

  Fly   224 QKSILPESACNIQ-FTSGTTGNPKAACLTHHNF------VNNGIHVGNRNELEGERICVQVPMFH 281
            ||:    :.|.:. :||||||.||...|:|.|.      |.....:.:::    |.:...:|:.|
Human   219 QKA----NQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDKH----ETVVSYLPLSH 275

  Fly   282 AFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNE-KCSVIHGTPTMYVDLVNTQKKLQV-PL 344
            ....::.|...:..||......|. :.|.:|.:.:.| |.:|..|.|.::..:....||... .:
Human   276 IAAQMMDIWVPIKIGALTYFAQAD-ALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSM 339

  Fly   345 GRIKKAVT-----GGAIVSPQLI-----------------KDVRQVLNVEAVHSVYG----LTET 383
            |..|||..     |..:.|.:::                 ..|:..|.::..||...    |.:.
Human   340 GLKKKAFVWARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQE 404

  Fly   384 TAVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVDAEG--RCVPFGQ----------------PGEL 430
            ||..|.||     |:.:..:..|::......:..:.  |.:..|:                .||:
Human   405 TAEFFLSL-----DIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEI 464

  Fly   431 CVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLI-RGGENIFPKEI 494
            |:.|....:||.:.|.:|.|.|.::.||.:||...|:..|:..:.|.:||:|| .||||:.|..:
Human   465 CLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPV 529

  Fly   495 EDFLNAHPQVIEAHVI----------------------GVPDERLGEEVCAYVRLEEGV-DPASF 536
            |..:.....:|...::                      |.|.::|..|...:.|   |: ..||.
Human   530 ETLVKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCR---GLGSQAST 591

  Fly   537 TAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVE 579
            ..|.:|  .:..|.:..:.:.:..::......:.:|:|:.::|
Human   592 VTEIVK--QQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	135/620 (22%)
		FACL_like_2	229..577	CDD:213284	90/424 (21%)
ACSBG2	NP_001276106.1	ACSBG_like	73..665	CDD:341256	127/593 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910