Protein Alignment Acsf2 and ACSF2

DIOPT Version :10

• Sequence 1: NP_608924.1
• Gene: Acsf2 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001275897.1
• Gene: ACSF2 / 80221
• HGNCID: 26101
• Length: 640
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 228/567 - (40%)
• Similarity: 344/567 - (60%)
• Gaps: 18/567 - (3%)

  Fly    23 RSISTSMPSLISHKHHIGKDPLVYRTIGQQLELSASNFGDVEAIVSCHEGKRYSFKSLLQEADAL 87
            |.:||.:..| |:.....|..|..:|:||.||.:|....:.||:|..||..|.:|..|.:|.|..
Human    74 RMVSTPIGGL-SYVQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKA 137

  Fly    88 AAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIA 152
            |:|...:||..||.:|:|.||...|.|..:..|:||:..|.:|||||..|:.|.|.||..||::.
Human   138 ASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVF 202

  Fly   153 PETFKTQNYYEILRDICPEISDADTGKIRSEKFPHLRSVI-IDSNDSLKGALRFDDFLDLASKSE 216
            |:.||||.||.:|:.||||:.:|..|.::|::.|.|.:|| :|:  .|.|.|..|:.  :|:.|.
Human   203 PKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDA--PLPGTLLLDEV--VAAGST 263

  Fly   217 REEVAKM---QKSILPESACNIQFTSGTTGNPKAACLTHHNFVNNGIHVGNRNEL-----EGERI 273
            |:.:.::   |:.:......||||||||||:||.|.|:|:|.|||...:|.|.:|     |..|:
Human   264 RQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRM 328

  Fly   274 CVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAIVNEKCSVIHGTPTMYVDLVNTQK 338
            .:..|::|..|.:...|..|..|||::|.:..|:.|.:|:||..|:.:.::|||||:||::|...
Human   329 ILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPD 393

  Fly   339 KLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSV 403
            .....:..:...|..|:...|:||:.:...:|::.:...||.||.:.|.|...|.|:.:....||
Human   394 FSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESV 458

  Fly   404 GHLTDHIEAKVVDAE-GRCVPFGQPGELCVRGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLE 467
            |.:..|.||::::.| |.......|||||:|||..||||..:.:||:|.:..|:|..|||...:.
Human   459 GRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMN 523

  Fly   468 ANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVRLEEGVD 532
            ..|:.:||||.|:|:|||||||:|.|:|||.:.||:|.|..|:||.|:|:|||:||.:||::|.:
Human   524 EQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEE 588

  Fly   533 PASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVE 579
            .   |.|.:||:.|||::|||:|:|::.:..:|.|.|||||||||.|
Human   589 T---TVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLRE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsf2	NP_608924.1	PRK08315	43..592	CDD:236236	222/547 (41%)
ACSF2	NP_001275897.1	PRK08315	82..640	CDD:236236	225/559 (40%)