Protein Alignment CG12512 and ACSM4

DIOPT Version :9

• Sequence 1: NP_608924.1
• Gene: CG12512 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001073923.1
• Gene: ACSM4 / 341392
• HGNCID: 32016
• Length: 580
• Species: Homo sapiens
• Alignment Length: 612
• Identity: 154/612 - (25%)
• Similarity: 249/612 - (40%)
• Gaps: 122/612 - (19%)

  Fly    27 TSMPSLISHKHHIGKDPLVYRTIGQQLELSASNFGDVEAIVSCHE--GKRYSFKS-LLQE----- 83
            |..|....||.|....||              ...|.|||..|:.  .|.::|.: :|.:
Human    16 TKPPGRRLHKDHQLWTPL--------------TLADFEAINRCNRPLPKNFNFAADVLDQWSQKE 66

  Fly    84 -----------------ADALAAGFRKL---------------GLQPGDAVGLWAPNYLHWYLGM 116
                             .|.:...||:|               |||.||.:.:..|....|:|..
Human    67 KTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVN 131

  Fly   117 MGAARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIR 181
            :...|.|:..:.........:|.|.|.....|.|:|.|            ::.|.:.....
Human   132 VACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASE------------EVAPAVESIVL---- 180

  Fly   182 SEKFPHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPK 246
              :.|.|::.::.|..|..|.|.|.:....||    ||.:.::..  .:....|.|||||||.||
Human   181 --ECPDLKTKLLVSPQSWNGWLSFQELFQFAS----EEHSCVETG--SQEPMTIYFTSGTTGFPK 237

  Fly   247 AACLTHHNFVNNGIHVGNRNELEGERICVQVPMFHAFGVII--------------SIMAALTKGA 297
            .|   .|:..:.||         |..:|.:..:......||              |:.::...||
Human   238 MA---QHSQSSLGI---------GFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGA 290

  Fly   298 -TMVLPAAGFSPKDSLQAIVNEKCSVIHGTPTMYVDLVNTQKKL-QVPLGRIKKAVTGGAIVSPQ 360
             ..|...|.|.....|..:.....:.:...||:|..||  ||.| :.....::..:|||..::|:
Human   291 CVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLV--QKDLKRYKFKSLRHCLTGGEPLNPE 353

  Fly   361 LIKDVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVDAEGRCVPFG 425
            :::..|....:| ::..||.|| ..:|..:..|  .::...|:|......:.:::|..|..:|.|
Human   354 VLEQWRVQTGLE-LYEGYGQTE-VGMICANQKG--QEIKPGSMGKGMLPYDVQIIDENGNVLPPG 414

  Fly   426 QPGELCV-----RGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRG 485
            :.||:.:     |.:.....|.|:.:||..||..|.:: |||:.|::::||...|||..:::|..
Human   415 KEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYV-TGDRGVMDSDGYFWFVGRADDVIISS 478

  Fly   486 GENIFPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVRLE---EGVDPASFTAETLKAYAKG 547
            |..|.|.|:|..|..||.|:|:.|:..||:..||.|.|:|.|.   :..:|...|.| |:.:.|.
Human   479 GYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLE-LQDHVKK 542

  Fly   548 KLAHFKVPRYVIPIDAFPKTTSGKIQK 574
            ..|.:|.||.|..:...|||.:|||::
Human   543 STAPYKYPRKVEFVQELPKTITGKIKR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	149/596 (25%)
		FACL_like_2	229..577	CDD:213284	106/370 (29%)
ACSM4	NP_001073923.1	MACS_euk	48..577	CDD:213294	142/566 (25%)
		Acs	49..580	CDD:223442	142/565 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910