DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12512 and Slc27a1

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_006509734.1	Gene:	Slc27a1 / 26457	MGIID:	1347098	Length:	657	Species:	Mus musculus

Alignment Length:	592	Identity:	142/592 - (23%)
Similarity:	234/592 - (39%)	Gaps:	122/592 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 AIVSCHEGKRYSFKSLLQEADALAAGFRKLGLQPGDAVGLW---APNYLHWYLGMMGAARAGLTS 126
            |:|....|..::|..|...::|:|..||:||..|||.|.::   .|.::..:||:   |:||:.:
Mouse   105 ALVDASSGICWTFAQLDTYSNAVANLFRQLGFAPGDVVAVFLEGRPEFVGLWLGL---AKAGVVA 166

  Fly   127 VGLNPAYQGPEIAYCLNKVNVKAII-------APETFKTQNYYEILR----DICPEISDADTGKI 180
            ..||...:...:|:||.....||:|       |......|....:|:    |:.||
Mouse   167 ALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDLGPE--------- 222

  Fly   181 RSEKFPHLRSVIIDSNDSLKGALRFDDFLD-LASKSEREEVAKMQKSILPESACNIQFTSGTTGN 244
                     |::.|:           ..|| :.:::....:|:.....:.:....| :||||||.
Mouse   223 ---------SILPDT-----------QLLDPMLAEAPTTPLAQAPGKGMDDRLFYI-YTSGTTGL 266

  Fly   245 PKAACLTHHNFVN---NGIHVGNRNELEGERICVQVPMFHAFGVIISIMAALTKGATMVLPAAGF 306
            ||||.:.|..:..   .|.|..:....:....|  :|::|:.|.|:.:...:..|.|:|| ...|
Mouse   267 PKAAIVVHSRYYRIAAFGHHSYSMRAADVLYDC--LPLYHSAGNIMGVGQCVIYGLTVVL-RKKF 328

  Fly   307 SPKDSLQAIVNEKCSVIH--GTPTMYVDLVNTQKKLQVPL------GRIKKAVTGGAIVSPQLIK 363
            |........|...|:|:.  |....|:        |:.|:      .|::.||..|  :.|.:.:
Mouse   329 SASRFWDDCVKYNCTVVQYIGEICRYL--------LRQPVRDVEQRHRVRLAVGNG--LRPAIWE 383

  Fly   364 DVRQVLNVEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSVGHLTDHI-EAKVV-----------D 416
            :..|...|..:...||.||....| .::.|.......||  .:..|: ..::|           |
Mouse   384 EFTQRFGVPQIGEFYGATECNCSI-ANMDGKVGSCGFNS--RILTHVYPIRLVKVNEDTMEPLRD 445

  Fly   417 AEGRCVPF--GQPGELC--------VRGYTTMLGYHDDEEKTKETI------GNDRWLRTGDQFV 465
            :||.|:|.  |:||.|.        :|.:.   ||..|....|:..      |:..:| :||..|
Mouse   446 SEGLCIPCQPGEPGLLVGQINQQDPLRRFD---GYVSDSATNKKIAHSVFRKGDSAYL-SGDVLV 506

  Fly   466 LEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAHPQVIEAHVIG--VPDERLGEEVCAYVRLE 528
            ::..||.....|..:.....|||:...|:|..|:......:..|.|  ||.......:.|.....
Mouse   507 MDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYGVAVPGVEGKAGMAAIADPH 571

  Fly   529 EGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLV-EAFKAKET------ 586
            ..:||.|...|..|.     ||.:..|.::..:.....|.:.||||.:|. |.|..::|
Mouse   572 SQLDPNSMYQELQKV-----LASYARPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFF 631

  Fly   587 -ELKAAR 592
             :||..|
Mouse   632 LDLKQGR 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	141/590 (24%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	95/388 (24%)
Slc27a1	XP_006509734.1	AFD_class_I	115..622	CDD:418409	135/564 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910