DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12512 and mug62

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_593037.1	Gene:	mug62 / 2541797	PomBaseID:	SPAC22F3.04	Length:	1428	Species:	Schizosaccharomyces pombe

Alignment Length:	404	Identity:	76/404 - (18%)
Similarity:	133/404 - (32%)	Gaps:	124/404 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 EGKRYSFKSLLQEADALAA-GFRKLGLQPGDAVGLW-----APNYLHWYLGMMGAARAGLTSVGL 129
            |...||:..:|..|...|: ....:||:||..|.|:     |..|:   :.:.|....|:..:.|
pombe   122 EAVSYSWDKILNRAKQFASVAQNHVGLKPGTRVILYYRKSEASEYI---ISIFGCLLLGIVVIPL 183

  Fly   130 NPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRS-----------E 183
            :|:.....:...:|:..|:.     .|.|:..|.|.      |.|.:....:|           .
pombe   184 SPSSSSESLKLVVNEEKVRV-----AFTTEATYRIF------IKDTEVNNAKSLAWWKSNDFTNY 237

  Fly   184 KFPHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNP-KA 247
            ||..::...:.:||::     ..|:...:|.....:.....|:.|.:..   ..||....|| :.
pombe   238 KFEQIKQYRMRANDTV-----LIDYTFSSSTYNDIKAVYTTKTFLSQMR---NLTSSMITNPARQ 294

  Fly   248 ACLTHHNFVNNGIHVGNRNELEGERICVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSL 312
            |....|||.::.                        .|:|:                .|.|...|
pombe   295 AGWKLHNFEDSK------------------------DVLIT----------------NFHPSMPL 319

  Fly   313 QAIVNEKCSVIHGTPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVLNVEAVHSV 377
            ..|:....||..|..|::.|    ::.|:.| |.:...:|                 .....:|:
pombe   320 GLIMGVFNSVFAGYCTIFCD----EEVLKTP-GLLAYLIT-----------------KYRCTYSL 362

  Fly   378 Y---GLTETTAVIFQSLPGDSSDVVLNSVGHLTD----HIEAKVVDAEGRCV-------PFGQPG 428
            :   ||.: |...:|..|..:.....|...:|:.    .:|.:|||.|...:       |.|...
pombe   363 FDYAGLKQ-TVYNYQEDPKSTLSFKKNYTPNLSSLKLCMVECEVVDPEFNIIVSDRWLQPLGTNN 426

  Fly   429 E-------LCVRGY 435
            .       ||:|.:
pombe   427 SKEVITPILCLRKF 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	76/404 (19%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	41/229 (18%)
mug62	NP_593037.1	AFD_class_I	117..731	CDD:302604	76/404 (19%)
		AMP-binding	120..599	CDD:278902	76/404 (19%)
		AFD_class_I	832..1379	CDD:302604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900