Protein Alignment CG12512 and DIP2C

DIOPT Version :9

• Sequence 1: NP_608924.1
• Gene: CG12512 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_011517730.1
• Gene: DIP2C / 22982
• HGNCID: 29150
• Length: 1626
• Species: Homo sapiens
• Alignment Length: 624
• Identity: 122/624 - (19%)
• Similarity: 213/624 - (34%)
• Gaps: 188/624 - (30%)

  Fly    80 LLQEADALAAGFRKLG-LQPGDAVGLWAPNYLHWYLGMMGAARAGLTSVGLNPAYQGPE-IAYCL 142
            |.:.|:.:|....:.| ||.||.|.|..|..:.......|...||...:.:.|.:  |: ||..|
Human  1067 LHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPH--PQNIATTL 1129

  Fly   143 NKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEK---------FPHLRSVIIDSNDS 198
              ..||.|:           |:.|..|...:......:||.:         :|    :|:|::|.
Human  1130 --PTVKMIV-----------EVSRSACLMTTQLICKLLRSREAAAAVDVRTWP----LILDTDDL 1177

  Fly   199 LKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTH---HNFVNNGI 260
            .|                 :..|::.|...|::...:.|:..|||......::|   ..|..:
Human  1178 PK-----------------KRPAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAATSAFCRS-- 1223

  Fly   261 HVGNRNELEGER-ICVQVPMFHAFGVIISIMAALTKG---------------ATMVLPAAGFSPK 309
             :..:.||...| :.:.:..:...|.::..:.::..|               |..:|..:.:..:
Human  1224 -IKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVR 1287

  Fly   310 DSLQAI-VNEKCSVIHGTPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQ------------L 361
            |:..:. |.|.|:...|:.|      .:.|...:.|.|::..|    :|:.:            |
Human  1288 DTFCSYSVMELCTKGLGSQT------ESLKARGLDLSRVRTCV----VVAEERPRIALTQSFSKL 1342

  Fly   362 IKDVRQVLNVEAVHSVYGLTETTAVIFQ------------------------------------- 389
            .||:.  |:..||.:.:|.....|:..|
Human  1343 FKDLG--LHPRAVSTSFGCRVNLAICLQPHRLWTLAEQGTSGPDPTTVYVDMRALRHDRVRLVER 1405

  Fly   390 ----SLPGDSSDVVLNSVGHLTDHIEAKVVDAEGRCVPFGQP--GELCVR------GYTTMLG-- 440
                |||...|..:|..|..:..:.|.|        .|.|..  ||:.|.      ||.|:.|
Human  1406 GSPHSLPLMESGKILPGVRIIIANPETK--------GPLGDSHLGEIWVHSAHNASGYFTIYGDE 1462

  Fly   441 -YHDDEEKTKETIGNDR--WLRTGDQFVL------EANGYGR----IVGRLKEMLIRGGENIFPK 492
             ...|...::.:.|:.:  |.|||....|      :|||...    :||.|.|.:...|....|.
Human  1463 SLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAMELRGMRYHPI 1527

  Fly   493 EIE-DFLNAHPQVIE------AHVIGVPDERLGEEVCAYVRLEEGVDPASFTAETLKAYAKGKLA 550
            :|| ..:.||..|.|      .:::.|..|..|.|       :|.:|........:..      .
Human  1528 DIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSE-------QEALDLVPLVTNVVLE------E 1579

  Fly   551 HFKVPRYVIPID--AFPKTTSGKIQKFKLVEAFKAKETE 587
            |:.:...|:.:|  ..|..:.|:.|:..|.:.|.|.:.:
Human  1580 HYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLD 1618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	122/624 (20%)
		FACL_like_2	229..577	CDD:213284	85/452 (19%)
DIP2C	XP_011517730.1	DMAP_binding	<32..180	CDD:283995
		CaiC	377..968	CDD:223395
		Dip2	401..965	CDD:213273
		AMP-binding	1036..1520	CDD:278902	99/511 (19%)
		AFD_class_I	1053..1615	CDD:302604	121/619 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900