Protein Alignment CG12512 and ACSF3

DIOPT Version :9

• Sequence 1: NP_608924.1
• Gene: CG12512 / 33766
• FlyBaseID: FBgn0031703
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_005256350.1
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 610
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 140/551 - (25%)
• Similarity: 222/551 - (40%)
• Gaps: 125/551 - (22%)

  Fly    60 FGDVEAIVSCHEGKRYSFKSLLQEADALAAGFRKL-GLQPGD----AVGLWAPNYLHWYLGMMGA 119
            |||..|:|..|  .|::::.|...:..|:....:| |...||    .|.....|...:.:....:
Human    53 FGDRIALVDQH--GRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWAS 115

  Fly   120 ARAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEK 184
            ..:|..:|.|...:...::.|.:.......::|     :|.|.|:|..:        ..|:....
Human   116 WMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLA-----SQEYLELLSPV--------VRKLGVPL 167

  Fly   185 FPHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPE-----SACNIQFTSGTTGN 244
            .|...::       ..||:              ||.|::.   :||     ....|.:||||||.
Human   168 LPLTPAI-------YTGAV--------------EEPAEVP---VPEQGWRNKGAMIIYTSGTTGR 208

  Fly   245 PKAACLTHHNF---VNNGIH--VGNRNELEGERICVQVPMFHAFGVIISIMAALTKGATMVLPAA 304
            ||....||.|.   |...:|  ...::::    |...:|:.|..||:.:::..|..|||.|: ..
Human   209 PKGVLSTHQNIRAVVTGLVHKWAWTKDDV----ILHVLPLHHVHGVVNALLCPLWVGATCVM-MP 268

  Fly   305 GFSPKDSLQAIVNE---KCSVIHGTPTMYVDLVN------TQKKLQ-----VPLGRIKKAVTGGA 355
            .|||:...:..::.   :.:|....||:|..|:.      ||...|     |...:|:..|:|.|
Human   269 EFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSA 333

  Fly   356 IVSPQLIKDVRQVLNVEAVHSV---YGLTE---------TTAVIFQSLPGDSSDVVLNSVGHLTD 408
            .:...:::..:.:..    |::   ||:||         ||||   .|||        |||....
Human   334 ALPLPVLEKWKNITG----HTLLERYGMTEIGMALSGPLTTAV---RLPG--------SVGTPLP 383

  Fly   409 HIEAKVV-----------------DAEGRCVPFG---QPGELCVRGYTTMLGYHDDEEKTKETIG 453
            .::.::|                 |..|..|..|   :.|||.|||.:....|.:..|:||....
Human   384 GVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFT 448

  Fly   454 NDRWLRTGDQFVLEANGYGRIVGRLKEMLIR-GGENIFPKEIEDFLNAHPQVIEAHVIGVPDERL 517
            .|.|.:|||..|.:...|. |.||....:|: ||..:...|:|..|.|||.:.:..||||||...
Human   449 LDGWFKTGDTVVFKDGQYW-IRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW 512

  Fly   518 GEEVCAYVRLEEGVDPASFTAETLKAYAKGK 548
            |:.|.|.|.|.||   .|.:...||.:|:.|
Human   513 GQRVTAVVTLREG---HSLSHRELKEWARLK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	140/551 (25%)
		FACL_like_2	229..577	CDD:213284	109/377 (29%)
ACSF3	XP_005256350.1	MCS	55..546	CDD:341264	138/549 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R434
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840