DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12512 and AgaP_AGAP000907

DIOPT Version :9

Sequence 1:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_316885.5	Gene:	AgaP_AGAP000907 / 1277421	VectorBaseID:	AGAP000907	Length:	553	Species:	Anopheles gambiae

Alignment Length:	479	Identity:	123/479 - (25%)
Similarity:	207/479 - (43%)	Gaps:	64/479 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 LNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRD------ICPEISDADTGKIRSEKFPH 187
            |:.|:...:.|:... |...|::    |...:..|::|:      |.|||      .:..|:...
Mosquito   118 LDTAFNVADFAHMFG-VTRPALV----FCESDILEVVREAAQRAAIAPEI------VLFEERTAG 171

  Fly   188 LRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACLTH 252
            .|.|:    |.|:.....|.|:..........||.:        .|    :|||||..|....||
Mosquito   172 YRHVL----DLLEPTGTEDSFVPTNLDDPTTHVAAV--------LC----SSGTTGLSKGVTYTH 220

  Fly   253 HNFVNNGIHVGNRNELEGERICVQVPMFHAFGVI--ISIMAALTKG----ATMVLPAAGFSPKDS 311
            ...:.|         |.............||..:  :|..|:|..|    |..|:..|.|:|..:
Mosquito   221 TFCIAN---------LPSLWRMAPTDCLLAFSSLYWLSGFASLIIGTVSQAARVITRAPFTPTLA 276

  Fly   312 LQAIVNEKCSVIHGTPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDVRQVL-NVEAVH 375
            |..:.....::...:|.....||:.....|.||..::..:.|||.||.||...:::.| :...:.
Mosquito   277 LDMLQRHPVTIAFFSPFQSNLLVHEPLLAQTPLPALRLFLCGGARVSKQLYAALQRCLPSHTRIQ 341

  Fly   376 SVYGLTETTAVIFQSLPGDSSDVVLNSVGHLTDHIEAKVVDAEG--RC--VPFGQPGELCVRGYT 436
            ..||::|:..|...    |.:....:.||.|...:||::|| :|  :|  .| .:|||:.:|...
Mosquito   342 IGYGMSESCLVTLT----DGNSYRDDCVGTLQARVEARIVD-DGLDQCGLAP-DEPGEIMLRVQI 400

  Fly   437 TMLGYHDDEEKTKETIGNDRWLRTGDQFVLEANGYGRIVGRLKEMLIRGGENIFPKEIEDFLNAH 501
            ...||:.:.:.|.|.:..|.|:||||....:.:|:..::.|.|:::...|..|.|.|:|......
Mosquito   401 PFAGYYGNPDATAELMSPDGWIRTGDIGYFDRDGHLYVIDRKKDIIKYAGNQISPTELEVLAKQL 465

  Fly   502 PQVIEAHVIGVPDERLGEEV-CAYVRLEEGVDPASFTAETLKAYAKGKL-AHFKVPRYVIPIDAF 564
            ..|::..|:|||||  |.:: .|.|..|.|...|:.||:.::.:...:: ||..:...|...:..
Mosquito   466 TGVLDCCVVGVPDE--GTDLPAALVLREPGATGAALTADQVRQFVDERVSAHKHLRGGVYFTEEM 528

  Fly   565 PKTTSGKIQKFKLVEAF-KAKETE 587
            |.|.||||.:.|.:|.. ||::::
Mosquito   529 PLTPSGKIVRRKCLEIVQKARQSK 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	123/479 (26%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	98/360 (27%)
AgaP_AGAP000907	XP_316885.5	CaiC	49..543	CDD:223395	120/468 (26%)
AgaP_AGAP000907	XP_316885.5	AFD_class_I	54..536	CDD:302604	117/461 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810