DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12512 and SLC27A5

DIOPT Version :9

Sequence 1:NP_608924.1 Gene:CG12512 / 33766 FlyBaseID:FBgn0031703 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_036386.1 Gene:SLC27A5 / 10998 HGNCID:10999 Length:690 Species:Homo sapiens


Alignment Length:576 Identity:133/576 - (23%)
Similarity:226/576 - (39%) Gaps:121/576 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 FGDVEAIVSCHEGKRYSFKSLLQEADALAAG----FRKLGLQPGDAVGLWAPNYLHWYLGMMGAA 120
            ||:::| .:|...  ::.|:.|.:..:|.||    ...|..|...|:.:|           :|.|
Human   145 FGELDA-RACQAA--WALKAELGDPASLCAGEPTALLVLASQAVPALCMW-----------LGLA 195

  Fly   121 RAGLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEKF 185
            :.|..:..:||..:|..:|:.:.....:.::.....:     |.|.:|.|        |:::|  
Human   196 KLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLR-----ESLEEILP--------KLQAE-- 245

  Fly   186 PHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGNPKAACL 250
             ::|...:.......|.......||.|  ......|.::..|...|.....:||||||.||.|.|
Human   246 -NIRCFYLSHTSPTPGVGALGAALDAA--PSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAIL 307

  Fly   251 THHNFVNNGIHVGNRNELEGERICVQVPMFHAFGVIISIMAALTKGATMVLPAAGFSPKDSLQAI 315
            ||...:.....:........:.:...:|::|..|:::.|:..|..|||.||     :||.|....
Human   308 THERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVL-----APKFSTSCF 367

  Fly   316 VNEKCSVIHG-TPTMYVD-----LVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDV----RQVLN 370
            .:: |.. || |..:||.     |.|..::.:.....::.|:..|      |..||    :|...
Human   368 WDD-CRQ-HGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNG------LRADVWETFQQRFG 424

  Fly   371 VEAVHSVYGLTETTAVIFQSLPGDSSDVVLNSVGH-------------------LTDHIEA--KV 414
            ...:..|||.||          |:..  ::|.||.                   :...:||  .|
Human   425 PIRIWEVYGSTE----------GNMG--LVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPV 477

  Fly   415 VDAEGRCVP--FGQPGELCVR--GYTTMLGYHDDEEKTKETI------GNDRWLRTGDQFVLEAN 469
            .|.:|.|:|  .|:||.|..:  .....:||....|.::..:      ..|.:..|||...::..
Human   478 RDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDRE 542

  Fly   470 GYGRIVGRLKEMLIRGGENIFPKEIE------DFLNAHPQVIEAHVIGVP--DERLGEEVCAYVR 526
            |:.....||.:.....|||:...|:|      |||    |.:..:.:.||  :.::|   .|.|:
Human   543 GFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFL----QQVNVYGVCVPGCEGKVG---MAAVQ 600

  Fly   527 LEEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLV-EAF 581
            |..|   .:|..|.|..:.:..|..:..|.::...||...|::.|:.|.:|| |.|
Human   601 LAPG---QTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGF 653

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12512NP_608924.1 PRK08315 43..592 CDD:236236 133/576 (23%)
FACL_like_2 229..577 CDD:213284 96/396 (24%)
SLC27A5NP_036386.1 PRK08279 87..690 CDD:236217 133/576 (23%)
hsFATP2a_ACSVL_like 140..680 CDD:213304 133/576 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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