DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vri and ddit3

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_005166228.1	Gene:	ddit3 / 561924	ZFINID:	ZDB-GENE-070410-90	Length:	242	Species:	Danio rerio

Alignment Length:	258	Identity:	61/258 - (23%)
Similarity:	98/258 - (37%)	Gaps:	62/258 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   504 PPSAGLYVPAPSAYKDHLEAAAAWSHNVEAAVSSSAVDAVSSSSVSGSAASVLNLSRRACS---- 564
            ||..|   |...|   .||   ||..:::              .:.||......|:|...|
Zfish     8 PPGVG---PLCGA---ELE---AWYEDLQ--------------DILGSDTGGAKLTRAPPSSEKE 49

  Fly   565 PSYEHMLSSTTSSTLSSASSSGAVSGDDEQ---EHEPAHMAPLQLQRSSPQQGSDANNCLP---L 623
            |.:..:|.|.:.:.|    :.|.|.||..|   |..|.|.:|.: |.....:.:.:.:.||   .
Zfish    50 PEFLDVLESCSLTWL----TEGQVWGDGVQRVTEDPPVHQSPPR-QEERTTENTSSGDLLPPEFF 109

  Fly   624 KLRHKSHLGD--------------KDAAATALLSLQHIKQEPNCSRA--------SPPAWNDGGD 666
            :|..:..:||              ...||:....|..:....:||.|        ||||  ....
Zfish   110 ELLSEGGVGDTMVNGGAGYHLHAPPSPAASEEEELPTVPDTSSCSSASRSPSLNCSPPA--SPPV 172

  Fly   667 NSSDERDSGISIASAEWTAQLQRKLLAPKEANVVTSAERDQMLKSQLERLESEVASIKMILAE 729
            :||.:|..|.::.||....:.:|:.....|..|....::::.||:::|||..||...:..|.|
Zfish   173 SSSRKRKRGGALCSASPGKKSRREREQENERKVQELTDQNERLKAEIERLGEEVQRTRRALIE 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842
vri	NP_001137792.1	coiled coil	239..297	CDD:269842
ddit3	XP_005166228.1	bZIP	<204..235	CDD:304365	9/30 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900