DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vri and Ddit3

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001103456.1	Gene:	Ddit3 / 29467	RGDID:	62391	Length:	168	Species:	Rattus norvegicus

Alignment Length:	121	Identity:	24/121 - (19%)
Similarity:	53/121 - (43%)	Gaps:	11/121 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 GGS-ISPQSNDSGMSDSLGKYVPGSGYGDGMMAQSPSQGGNGPQSALTAAQKELFSQRKQREFTP 234
            ||: ||...|:...|.:.....|.|   ...:.:.|     ||....:.:|........|.....
  Rat    35 GGTYISSPGNEEEESKTFTTLDPAS---LAWLTEEP-----GPAEVTSTSQSPRSPDSSQSSMAQ 91

  Fly   235 DNKKDESYWDRRRRNNE--AAKRSREKRRYNDMVLEQRVIELTKENHVLKAQLDAI 288
            :.::::....|:|:.:.  ||:..:::.:..:...|::|.:|.:||..||.:::.:
  Rat    92 EEEEEDQGRTRKRKQSGQCAARAGKQRMKEKEQENERKVAQLAEENERLKQEIERL 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842	11/53 (21%)
vri	NP_001137792.1	coiled coil	239..297	CDD:269842	11/52 (21%)
Ddit3	NP_001103456.1	N-terminal. /evidence=ECO:0000250	10..26
		Interaction with TRIB3. /evidence=ECO:0000250	10..18
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..130		18/102 (18%)
		coiled coil	98..152	CDD:269834	11/50 (22%)
		BRLZ	100..160	CDD:197664	11/48 (23%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	100..129		5/28 (18%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	133..147		5/13 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810