DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vri and Hlf

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_006533067.1	Gene:	Hlf / 217082	MGIID:	96108	Length:	296	Species:	Mus musculus

Alignment Length:	187	Identity:	56/187 - (29%)
Similarity:	87/187 - (46%)	Gaps:	41/187 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 SNISPTLSMNGSSNEASNLHPLSMYGGSISPQSNDSGMSDSLGKYVPGS---------------- 194
            |:.:|:: |:.||...:.|||     |..||....|.:..  |:.:|.:
Mouse   117 SSTAPSV-MDLSSRATAPLHP-----GIPSPNCMQSPIRP--GQLLPANRNTPSPIDPDTIQVPV 173

  Fly   195 GY----GDGMMAQSPSQGGNGPQSALTAAQKELFSQ---RKQRE-FTPDN-KKDESYWDRRRRNN 250
            ||    .|..::..|.|....|:.. ..:::||..|   :|.|: |.||: |:|:.||.|||:||
Mouse   174 GYEPDPADLALSSIPGQEMFDPRKR-KFSEEELKPQPMIKKARKVFIPDDLKQDDKYWARRRKNN 237

  Fly   251 EAAKRSREKRRYNDMVLEQRVIELTKENHVLKAQLDAIRDKFNISGENLVSVEKILA 307
            .||||||:.||..:..:..|...|.|||..|:.::..:|       :.|...:.|||
Mouse   238 MAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLR-------KELGKCKNILA 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842	23/58 (40%)
vri	NP_001137792.1	coiled coil	239..297	CDD:269842	23/57 (40%)
Hlf	XP_006533067.1	bZIP_HLF	226..284	CDD:269843	24/64 (38%)
Hlf	XP_006533067.1	coiled coil	226..284	CDD:269843	24/64 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810