DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vri and Jun

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_034721.1	Gene:	Jun / 16476	MGIID:	96646	Length:	334	Species:	Mus musculus

Alignment Length:	185	Identity:	44/185 - (23%)
Similarity:	62/185 - (33%)	Gaps:	43/185 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 KILASLPTSEQVLSNTKRAKMSGSGGSSSGSSPSGSGSGEGSPQGGHNGYPVGPPLSPLIYGPNG 368
            :.||.|.:...:.|.|..|:.....|..:.:..|.:|:      ||..||.......|.:|....
Mouse   116 RALAELHSQNTLPSVTSAAQPVSGAGMVAPAVASVAGA------GGGGGYSASLHSEPPVYANLS 174

  Fly   369 NARPEATVKSVHHIHHAGVAPPPTHLQQLVVPQSQTQHLYQPQPQQHQPHQQQQIS-QPPQQQQQ 432
            |..|.|.        .:|...|......|..|....|....|||..|.|   |||. |.|:.|..
Mouse   175 NFNPGAL--------SSGGGAPSYGAAGLAFPSQPQQQQQPPQPPHHLP---QQIPVQHPRLQAL 228

  Fly   433 QQEPSPSAGSSSPVISDPHNRPPSTTIANLQVQLQQALNRNVRPEDLDSLRKVVA 487
            ::||       ..|...|...||                  :.|.|::|..::.|
Mouse   229 KEEP-------QTVPEMPGETPP------------------LSPIDMESQERIKA 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842
vri	NP_001137792.1	coiled coil	239..297	CDD:269842
Jun	NP_034721.1	Jun	5..244	CDD:309180	38/151 (25%)
		Interaction with PAGE4. /evidence=ECO:0000250\|UniProtKB:P05412	150..226		25/92 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..217		8/28 (29%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	255..282		1/4 (25%)
		bZIP_Jun	257..317	CDD:269844	1/2 (50%)
		coiled coil	258..309	CDD:269844	1/1 (100%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	283..311
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910