DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vri and Dbp

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_058670.2	Gene:	Dbp / 13170	MGIID:	94866	Length:	325	Species:	Mus musculus

Alignment Length:	215	Identity:	59/215 - (27%)
Similarity:	88/215 - (40%)	Gaps:	46/215 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 PRPPTGGKEEKLLLLAPPGKLYPEASVSTAMPEVLSGTPTNSHNKANIAMMNNVRLSNISPTLSM 154
            |.||            |||.|.|..|.:.        ||..|....:        .|:.||..|.
Mouse   130 PSPP------------PPGGLSPAPSPAR--------TPAPSPGPGS--------CSSSSPRSSP 166

  Fly   155 NGSSNEASNLHPLSMYGG-------SISPQSNDSGMSDSLGKYVPGSGYGDGMMAQSPSQGGNGP 212
            ..:...|:    |...||       ..:|...|....:.|..:.|..  .|..::..|......|
Mouse   167 GHAPARAT----LGAAGGHRAGLTSRDTPSPVDPDTVEVLMTFEPDP--ADLALSSIPGHETFDP 225

  Fly   213 QSALTAAQKELFSQ---RKQREF-TPDNKKDESYWDRRRRNNEAAKRSREKRRYNDMVLEQRVIE 273
            :.. ..:::||..|   :|.|:. .|:.:|||.||.||.:|||||||||:.||..:..:..|...
Mouse   226 RRH-RFSEEELKPQPIMKKARKVQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAF 289

  Fly   274 LTKENHVLKAQLDAIRDKFN 293
            |.|||.:|:.::.|:|.:.:
Mouse   290 LEKENALLRQEVVAVRQELS 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842	26/56 (46%)
vri	NP_001137792.1	coiled coil	239..297	CDD:269842	25/55 (45%)
Dbp	NP_058670.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..98
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..203		22/104 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..256		7/25 (28%)
		bZIP_HLF	254..313	CDD:269843	26/56 (46%)
		coiled coil	255..313	CDD:269843	25/55 (45%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	257..279		15/21 (71%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	283..297		5/13 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810