DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vri and BATF2

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_612465.3	Gene:	BATF2 / 116071	HGNCID:	25163	Length:	274	Species:	Homo sapiens

Alignment Length:	300	Identity:	63/300 - (21%)
Similarity:	102/300 - (34%)	Gaps:	97/300 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 GGNGPQSALTAAQKELFSQRKQREFTPDNKKDESYWDRRRRNNEAAKRSREKRRYNDMVLEQRVI 272
            ||||           |.:|...:|.....||        ::|..||:|||:|.......|.|:..
Human     5 GGNG-----------LLTQTDPKEQQRQLKK--------QKNRAAAQRSRQKHTDKADALHQQHE 50

  Fly   273 ELTKENHVLKAQLDAIRDKFNISGENLVSVEKILASLPTSEQVLSNTKRAKMSGSGGSSSGSSPS 337
            .|.|:|..|:.::.:::.:.......|...|::...                    ..:|.|:|.
Human    51 SLEKDNLALRKEIQSLQAELAWWSRTLHVHERLCPM--------------------DCASCSAPG 95

  Fly   338 GSG---SGEG----SPQGGH-------------NGYPVGPPLSPLIYGPNGNARP---EATVKSV 379
            ..|   ..||    .|||.|             :.|| ..||||   ||..:..|   :..:.|:
Human    96 LLGCWDQAEGLLGPGPQGQHGCREQLELFQTPGSCYP-AQPLSP---GPQPHDSPSLLQCPLPSL 156

  Fly   380 HHIHHAGVAPPPTHL--------------------QQLVVPQSQTQHLYQPQPQQHQPHQQQQIS 424
             .:..|.||.||..|                    :...:..|.|.....|||.:.:...:.::.
Human   157 -SLGPAVVAEPPVQLSPSPLLFASHTGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLG 220

  Fly   425 QPPQQ----------QQQQQEPSPSAGSSSPVISDPHNRP 454
            ..|..          |.::.:|:.||.:...::.||...|
Human   221 SSPDNPSSALGLARLQSREHKPALSAATWQGLVVDPSPHP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842	14/58 (24%)
vri	NP_001137792.1	coiled coil	239..297	CDD:269842	13/57 (23%)
BATF2	NP_612465.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..47		17/60 (28%)
		bZIP_BATF	17..74	CDD:269849	16/64 (25%)
		coiled coil	19..73	CDD:269849	15/61 (25%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	20..41		9/28 (32%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	45..66		6/20 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..151		9/26 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..229		6/41 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910