DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vri and atf2

DIOPT Version :9

Sequence 1:	NP_001137792.1	Gene:	vri / 33759	FlyBaseID:	FBgn0016076	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_009302699.1	Gene:	atf2 / 100006516	ZFINID:	ZDB-GENE-030911-8	Length:	488	Species:	Danio rerio

Alignment Length:	387	Identity:	86/387 - (22%)
Similarity:	132/387 - (34%)	Gaps:	132/387 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 SGSDFPYGPRPPTGGKEEKLLLLAPPGKLYPEASV---STAMPEVLSG-------------TPTN 130
            |..|.|. |.|.:...::|.:.|.|| .|.|...|   |..:|.||..             :||:
Zfish   113 SHRDSPL-PHPESTTTDDKEVSLQPP-SLPPSTIVRPPSLQVPNVLLANSEAGVVIQQALPSPTS 175

  Fly   131 SHNKANIAMMNN--VRLSNISPTLSM--NG--------SSNEASNLH-----PL--------SMY 170
            |....::...:.  |.:|...|.|..  ||        ::..:|::|     ||        |:.
Zfish   176 SSVITHVPSSSRPIVPVSGTFPVLLQLPNGQTMPVAIPATIASSSVHIPTAIPLVRPVTVVPSVP 240

  Fly   171 G--GSISPQSNDS----GMSDSLGKYVPGSGYGDGMMAQSPSQGGNGPQSALTAAQKELFSQRKQ 229
            |  |..|||...|    .:..:|.:.:|....||.:..||.|.....|.:...|.::...|.::.
Zfish   241 GIPGPASPQPVQSEAKMKLKAALSQQIPQVTNGDAIDIQSSSASETPPPAPPPAEEQRPKSLQQP 305

  Fly   230 REFT--------PDNKKDESYWDRRR----------------RNNEAAKRSREKRRYNDMVLEQR 270
            ...|        |..:...|...|||                ||..||.|.|:||:.....||::
Zfish   306 ATSTTEIPVSPAPPAQHTPSTGGRRRRTTSEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKK 370

  Fly   271 VIELTKENHVLKAQLDAIR------------------------------DKFNISGENLVSVEKI 305
            ..:|:..|..|:.::..:|                              ||.:..||..|
Zfish   371 AEDLSSVNGQLQNEVTLLRNEVAQLKQLLLAHKDCPVTLLQKKSGYQPLDKEDSCGEMSV----- 430

  Fly   306 LASLPTSEQVLSNTKRAKMSGSGGSSS--------GSSPSGSGSGE-----------GSPQG 348
             .|.|.:|.:    :.:.:|.|.|.||        .|||:...:.|           |.|.|
Zfish   431 -PSSPQNEAI----QHSSISTSNGVSSSTAASVLTASSPAAGAAAEPSTEDEDEDELGQPSG 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vri	NP_001137792.1	bZIP_NFIL3	238..297	CDD:269842	20/104 (19%)
vri	NP_001137792.1	coiled coil	239..297	CDD:269842	20/103 (19%)
atf2	XP_009302699.1	C2H2 Zn finger	9..31	CDD:275370
		GCN4_cent	47..84	CDD:213399
		bZIP_ATF2	341..401	CDD:269835	14/59 (24%)
		coiled coil	341..401	CDD:269835	14/59 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910