DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP96A8

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_175193.1	Gene:	CYP96A8 / 841171	AraportID:	AT1G47620	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	120/539 - (22%)
Similarity:	222/539 - (41%)	Gaps:	110/539 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 WLLLRQLNKTY-----------FILSLCKRVRTADGSPLESKVFVVPGKTRFGNNLDLL-NLTPA 68
            :||:::..::|           .:|...:|:.......||:.......|..:...:|:| .:.||
plant    30 YLLIKKTLQSYPWNWPVLGMLPGVLLRLQRIYDCSVEVLENSNMTFQFKGPWFVGMDVLATVDPA 94

  Fly    69 NIFSYIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLI 133
            ||...:     .:|..|||...:|            .|||::                .|||::.
plant    95 NIHHIM-----SSNFSNYIKGPIF------------HEIFEA----------------FGDGIIN 126

  Fly   134 SIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKILD---------KNVGFELELNQIIPQ 189
            :..:.|...|......|:....|:|     ..|....|:.|         .|....::|..:..:
plant   127 TDAELWRDWRNASQLIFNHQRYQNF-----SASTTKTKVNDGLVPLFNHFANEEIVVDLEDVFQR 186

  Fly   190 F----TLNNICET---ALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPLMFFNW---YFFLFGD 244
            |    |...|..|   :|.:::.::    |:.||:.|.......|...|.  |.|   .:...|.
plant   187 FMYDITFIFITGTDPRSLSIEMPEV----EFSKALDDVGDAIVHRHITPR--FVWKLQKWIGIGT 245

  Fly   245 YKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQ--VDEFGKKQRYAMLDTLLAAEAEG----KID 303
            .||..:...|.......||..||:     :||.  :......:|..:|.:.:..:|..    |..
plant   246 EKKMLKAHATFDRVCEKIIAAKRE-----ELGSQGITYNSNGEREDLLTSFIKLDATKYEVLKPS 305

  Fly   304 H-QGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQ-DLPEDIDEVSMFQF-NEL 365
            | :.:.|....||..|.|:|:::|.:....|:.:.:|..:..:|:. :||....:..|..: |:|
plant   306 HDKFLRDFTIGFMAAGRDSTASTLTWFFWNLSKNPNVLTKILQEINTNLPRTGSDQDMSSYLNKL 370

  Fly   366 IHLECVIKESLRLFPSAPIIGRTCIEESVM-NGLVLPKNAQISIHIYDIMR-------DARHFPK 422
            ::|...:.||:||:|..|...::.|:|.|: :|..:..|..|.|.||.:.|       ||.
plant   371 VYLHGALSESMRLYPPIPFQRKSPIKEDVLPSGHKVKSNINIMIFIYAMGRMKTIWGEDAM---- 431

  Fly   423 PNQFLPERFLPENSVNRH--PFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF--KLLPATQL 483
              :|.|||::.|....||  .:.|:.|:||||.|:|:...:..:|.::..:::|:  |::...::
plant   432 --EFKPERWISETGGVRHEPSYKFLSFNAGPRTCLGKNLAMNLMKTVIVEILQNYEIKIVSGQKI 494

  Fly   484 EDLTFENGIVLRTQQNIKV 502
            |.   :.|::|..:..:||
plant   495 EP---KPGLILHMKHGLKV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	113/493 (23%)
CYP96A8	NP_175193.1	p450	1..515	CDD:386267	120/539 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010