DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP86C1

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_173862.1	Gene:	CYP86C1 / 839069	AraportID:	AT1G24540	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	123/514 - (23%)
Similarity:	239/514 - (46%)	Gaps:	66/514 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FILSLCKRVRTADGSPLESKVF-VVPGKTRFGNNLDLLNLTPANIFSYIRESTAKANGQNYIWNF 90
            |:||..:....:.|.|:...|. ::|          :|.|...::|::......::.|..:....
plant    28 FLLSYLREKLVSKGGPVMWPVLGIIP----------MLALNKHDLFTWCTRCVVRSGGTFHYRGI 82

  Fly    91 LFAPEYNIVRAEDA--EEIFQST-KITTKNMSY-ELIRPFLGDGLLISIDQKWHTRRKTLTPAFH 151
            .|...|.|:.|:.|  |.|.::. |...|...| |..|..|.||:..:.|:.|...|:......|
plant    83 WFGGAYGIMTADPANVEHILKTNFKNYPKGAFYRERFRDLLEDGIFNADDELWKEERRVAKTEMH 147

  Fly   152 FN--ILQSFLSIFKEESKKFIKILD-----KNVGFELELNQIIPQFTLNNICETALGVKLDDMSE 209
            .:  :..:|.::.....:|.:.:::     |.|   .:|..::.:||.:|||.:|.||....:..
plant   148 SSRFLEHTFTTMRDLVDQKLVPLMENLSTSKRV---FDLQDLLLRFTFDNICISAFGVYPGSLET 209

  Fly   210 G---NEYRKAIHD-FEIVFNQRMCNPLMFFNWYFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQF 270
            |   ..:.||..| .|....:.:..|.::....|...|..:|.:..:|.:|.|::..::.:|.
plant   210 GLPEIPFAKAFEDATEYTLARFLIPPFVWKPMRFLGIGYERKLNNAVRIVHAFANKTVRERRN-- 272

  Fly   271 KQKQLGQVDEFGKKQRYAMLDTLLAAEAEGKID-----------HQGICDEVNTFMFGGYDTTST 324
            |.::||.::::..     :|..|:..|.|.:.|           .:..|   .:|:..|.||||.
plant   273 KMRKLGNLNDYAD-----LLSRLMQREYEKEEDTTRGNYFSDKYFREFC---TSFIIAGRDTTSV 329

  Fly   325 SLIFTLLLLALHADVQERCYEELQDL------PEDIDEVSMFQFNELIHLECVIKESLRLFPSAP 383
            :|::...|:..|.:|::|...|::::      .|..|:.....|.|:::|:..:.|||||:||.|
plant   330 ALVWFFWLVQKHPEVEKRILREIREIKRKLTTQETEDQFEAEDFREMVYLQAALTESLRLYPSVP 394

  Fly   384 IIGRTCIEESVM-NGLVLPKNAQISIHIYDIMRDARHFPKP-NQFLPERFLPENS-VNRHPFAFV 445
            :..:..:|:.|: :|..:.|.|:|...:|.:.|....:.|. .:|.|||::.|.. |:...|.:|
plant   395 MEMKQALEDDVLPDGTRVKKGARIHYSVYSMGRIESIWGKDWEEFKPERWIKEGRIVSEDQFKYV 459

  Fly   446 PFSAGPRNCIGQKFGVLEIKVLLAAVIRNF--KLLPATQL-----EDLTFENGIVLRTQ 497
            .|:.|||.|:|:||...::|::.||::..:  |::...::     ..|..:||:.:..|
plant   460 VFNGGPRLCVGKKFAYTQMKMVAAAILMRYSVKVVQGQEIVPKLTTTLYMKNGMNVMLQ 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	117/489 (24%)
CYP86C1	NP_173862.1	p450	90..520	CDD:299894	110/442 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920