DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP71A18

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001184964.1	Gene:	CYP71A18 / 837705	AraportID:	AT1G11610	Length:	504	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	110/499 - (22%)
Similarity:	202/499 - (40%)	Gaps:	63/499 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWIALLGSSLLIGALWLLLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKTRFGNNLDLLNL 65
            |.:.|:.|..|...|.|||  |.|  |:....|:|..   .|...::.|:       .||..|:|
plant     1 MEMTLMVSLCLTTLLTLLL--LKK--FLKRTAKKVNL---PPSPWRIPVI-------GNLHQLSL 51

  Fly    66 TPANIFSYIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNM-SYELIRPFLGD 129
            .|....    .|.:...|...:.:|...|...:..:|.|.||.::..:...|. ..:.:...:..
plant    52 HPHRSL----HSLSLRYGPLMLLHFGRVPILVVSSSEAAHEILKTHDLKFANRPKSKAVHGLMNG 112

  Fly   130 G---LLISIDQKWHTRRKTLTPAFHFNIL-----QSFLSIFKEESKKFIKILDK-NVGFELE-LN 184
            |   :.....:.|...:....    .|:|     .||..:.:||....::.|:| :.....| |:
plant   113 GRDVVFGPYGEYWRQMKSVCI----LNLLTNKMVASFEKVREEEVNAMMEKLEKASCSSSAENLS 173

  Fly   185 QIIPQFTLNNICETALGVKL-DDMSEGNEYRKAIHDFEIVFNQRMCNPLMFFNWYFFLFGDYKKY 248
            ::....|.:.....:||.|. :|.:.|...::.....|::..              |..|||...
plant   174 ELFVTLTSDVTSRVSLGKKYWEDETAGGLKKRVRQIMELLRE--------------FPIGDYVPA 224

  Fly   249 SRILRTIHGFSSGIIQ--RKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAEAEG----KIDHQGI 307
            ...:..|:||:|.|::  |......:|.:.:..|.| :.:...::.||:.|.|.    |:....|
plant   225 LAWIDRINGFNSKIVEVSRAYSDLMEKVVQEHLEAG-EHKADFVNILLSIEKEKNNGFKVQRNDI 288

  Fly   308 CDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDL--PEDIDEVSMFQFNELIHLEC 370
            ...:.....||..|:||.|.:.:..|..:.:..::...|::..  |.. ..:...:...:.:|:.
plant   289 KFMILDMFIGGISTSSTLLEWIMTELIRNPECMKKLQNEIRSTIRPHG-SYIKEKEVENMRYLKA 352

  Fly   371 VIKESLRLFPSAP-IIGRTCIEESVMNGLVLPKNAQISIHIYDIMRD-ARHFPKPNQFLPERFLP 433
            ||||..|:.|..| |:.|...|:..:.|..:....::.|:.:.|.|| |...|...:|.|||.|
plant   353 VIKEVFRVHPPLPLILPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHL- 416

  Fly   434 ENSVNRH--PFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF 475
            :::::.|  ...::||.:|.|.|.|....:..::|.||.::..|
plant   417 DSTLDYHGQDLKYIPFGSGRRICPGINLAMGLVEVTLANLVGRF 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	95/449 (21%)
CYP71A18	NP_001184964.1	p450	26..496	CDD:299894	99/470 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010