DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP94B1

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001331365.1	Gene:	CYP94B1 / 836464	AraportID:	AT5G63450	Length:	568	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	125/536 - (23%)
Similarity:	229/536 - (42%)	Gaps:	75/536 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LIGALWLLLRQLNKTYFILSL-CKRVRTADGSPLESKVFVVPGK-TRFGNN--------LDLLNL 65
            ::.|:.|:|..:.....|.|. .|.::....||.....:.:.|. ..|..|        .|||.|
plant    61 MLNAIILILFPIIGFVLIFSFPTKTLKAKTASPSNPTSYQLIGSILSFNKNRHRLLQWYTDLLRL 125

  Fly    66 TPANIFS----YIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPF 126
            :|:...:    :.|.:...||.:| :.:.|....||          |...|..|     :|:...
plant   126 SPSQTITVDLLFGRRTIITANPEN-VEHILKTNFYN----------FPKGKPFT-----DLLGDL 174

  Fly   127 LGDGLLISIDQKWHTRRKTLTPAFHFNILQSF-LSIFKEE-SKKFIKILDKNV--GFELELNQII 187
            ||.|:..|..:.|.::||..:..|....|:.| ..|.:|| ..:.|.:|...|  |..::..:::
plant   175 LGGGIFNSDGELWSSQRKLASHEFTMRSLREFTFEILREEVQNRLIPVLSSAVDCGETVDFQEVL 239

  Fly   188 PQFTLNNICETALGVKLDDMSEGNEYRKAIHDFEIV--FNQRMCNPLMFFNW---YFFLFGDYKK 247
            .:|..:.:|:.:||...|.:.......:.:..|::.  .:.|.....::..|   .|...|..|:
plant   240 KRFAFDVVCKVSLGWDPDCLDLTRPVPELVKAFDVAAEISARRATEPVYAVWKVKRFLNVGSEKR 304

  Fly   248 YSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAEAEGKIDHQGICDEVN 312
            ....::|:|...|.||:.|:     |.|....:...||  .:|...||| ..|:   :.:.|.|.
plant   305 LREAIKTVHLSVSEIIRAKK-----KSLDIGGDVSDKQ--DLLSRFLAA-GHGE---EAVRDSVI 358

  Fly   313 TFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDLP------EDIDEVSMFQFNELIHLECV 371
            :|:..|.||||.::.:...||:.:.||:.:..:||::..      ||:.|:|        :.:..
plant   359 SFIMAGRDTTSAAMTWLFWLLSQNDDVETKILDELRNKGSLGLGFEDLREMS--------YTKAC 415

  Fly   372 IKESLRLFPSAPIIGRTCIEESVM-NGLVLPKNAQISIHIYDIMRDARHFPKP-NQFLPER-FLP 433
            :.|::||:|......:....:.:: :|..|.|..:::...|.:.|..:.:.|. ::|.|.| |..
plant   416 LCEAMRLYPPVAWDSKHAANDDILPDGTPLKKGDKVTYFPYGMGRMEKVWGKDWDEFKPNRWFEE 480

  Fly   434 ENSVNRHP-------FAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDLTFENG 491
            |.|....|       |.|..|.||||.|||::....::|.::.:|:..||::|......: |...
plant   481 EPSYGTKPVLKSVSSFKFPVFQAGPRVCIGKEMAFTQMKYVVGSVLSRFKIIPVCNNRPV-FVPL 544

  Fly   492 IVLRTQQNIKVKFEAR 507
            :.......:|||.:.|
plant   545 LTAHMAGGLKVKIKRR 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	115/490 (23%)
CYP94B1	NP_001331365.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920