DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP96A4

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_200045.1	Gene:	CYP96A4 / 835308	AraportID:	AT5G52320	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	122/528 - (23%)
Similarity:	207/528 - (39%)	Gaps:	105/528 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LIGALWLLLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKTRFGNNLDLLNLTPANIFSYIR 75
            ::|.|..:|.|:.:.|..::.........|      .|:.|..:  |.:: ||.:.|.|| .||.
plant    39 VLGMLPGVLFQIPRIYDFVTEALEAENMTG------CFIGPWLS--GTDI-LLTVDPVNI-QYIL 93

  Fly    76 ESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLISIDQKWH 140
            .|           ||:..|                     |...:..|..|||||:.......|.
plant    94 SS-----------NFVNYP---------------------KGKKFNKIFEFLGDGIFNVDSGLWE 126

  Fly   141 TRRKTLTPAFHFNILQSF---LSIFKEESKKFIKILDKNVGFEL--ELNQIIPQFTLNNICETAL 200
            ..|.:....|.....|||   .|:.| .|:..:.|||..|...:  :|..:..:|..:.......
plant   127 DMRNSSHAIFSHQDFQSFSVSTSVSK-LSQGLVPILDNAVEKHILVDLQDLFQRFLFDTSSTLMA 190

  Fly   201 GVKLDDMS---EGNEYRKAIHDFEIVFNQRMCNPLMFFNWYFFL-FGDYKKYSRILRTIHGFSSG 261
            |.....:|   ...|:..|:.........|...|...::...:: .|..||..|.|.........
plant   191 GYDPKSLSVEMPKVEFADAMDGVADAMFYRHLKPAFLWSIQSWIGVGIEKKMRRGLDVFDQMLGK 255

  Fly   262 IIQRKRQQFKQKQLGQVDEFGKKQ----RYAMLDTLLAAEAEGKIDHQGICDEVNTFMFGGYDTT 322
            ||..||::.|..  |..|..|:..    .|..:||......:...| :.|.|.:...:....|||
plant   256 IISAKREEIKNH--GIHDSKGEAMDVLTYYMTIDTTKYKHLKPSND-KFIRDTILGLVIAARDTT 317

  Fly   323 STSLIFTLLLLALHADVQERCYEELQDL-----PEDIDEVSMFQFNELIHLECVIKESLRLFPSA 382
            |::|.:...||:.:.:...:..:|:...     |.|:|        :|::|:..:.|:|||:||.
plant   318 SSALTWFFWLLSKNPEAMTKIRQEINKKMPKFDPADLD--------KLVYLDGAVCETLRLYPSV 374

  Fly   383 PIIGRTCIEESVM-NGLVLPKNAQISIHIYDIMR-------DARHFPKPNQFLPERFLPENSVNR 439
            |...::..:..|: :|..:.||.::.|.||.:.|       ||      ..|.|||::.::.:.|
plant   375 PFNHKSPAKPDVLPSGHKVDKNWRVVIPIYSLGRMKSVWGDDA------EDFRPERWISDSGMLR 433

  Fly   440 H--PFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDLTFENG--------IVL 494
            .  .:.|:.|:||||.|:|::...|::|.:...:|||:         |:....|        ::|
plant   434 QESSYKFLAFNAGPRTCLGKRLTFLQMKTVAVEIIRNY---------DIKVVEGHKPKPVPSVLL 489

  Fly   495 RTQQNIKV 502
            |.|..:||
plant   490 RMQHGLKV 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	115/488 (24%)
CYP96A4	NP_200045.1	p450	1..501	CDD:416425	122/528 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920